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Supplier NameMedChemExpress (MCE)
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Emailsales@medchemexpress.com; tech@medchemexpress.com
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Product NameCoumarin 106
SynonymsCoumarin 106
CAS41175-45-5
EINECS
Chemical FormulaC18H19NO2
Molecular Weight281.35
inchi
Package10 mg;25 mg;50 mg;100 mg
PriceEmail to quote
DescriptionsCoumarin 106

Coumarin 106

MedChemExpress (MCE)

HY-W324391

41175-45-5

Coumarin 478

99.76%

4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months

Descriptions

Coumarin 106

Coumarin 106

MedChemExpress (MCE)

HY-W324391

41175-45-5

Coumarin 478

99.76%

4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months
-20°C, 1 month (sealed storage, away from moisture and light)

Room temperature in continental US
may vary elsewhere.

Coumarin 106 (Coumarin 478) is a dipolar laser dye. Coumarin 106 is an inhibitor of AChE and BChE. Coumarin 106 displays mixed-type AChE inhibition with a pIC50=4.97 and Ki=2.36 μM. Coumarin 106 inhibits BChE with slightly lower potency (pIC50=4.56).

Coumarin 106 is non-toxic in Caco-2 cells[2].

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[1]. Patil SK, et al. Determination of ground and excited state dipole moments of dipolar laser dyes by solvatochromic shift method. Spectrochim Acta A Mol Biomol Spectrosc. 2014 Apr 5
123:117-26. [Content Brief]

[2]. Fallarero A, et al. Inhibition of acetylcholinesterase by coumarins: the case of coumarin 106. Pharmacol Res. 2008 Sep-Oct
58(3-4):215-21. [Content Brief]

Last Update2025-04-01 14:45:47
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