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Supplier Contact

Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
Wechat
Product Namearctiin
Synonymsarctiin
ARCTIIN
ARCTIIN(P)
(-)-ARCTIIN
Arctiin (8CI)
(-)-Arctin,Arctiumlappa
ARCTIGENIN-O-BETA-D-GLUCOPYRANOSIDE

Synonyms

arctiin
ARCTIIN
ARCTIIN(P)
(-)-ARCTIIN
Arctiin (8CI)
(-)-Arctin,Arctiumlappa
ARCTIGENIN-O-BETA-D-GLUCOPYRANOSIDE
4-{[(3R,4R)-4-(3,4-dimethoxybenzyl)-2-oxotetrahydrofuran-3-yl]methyl}-2-methoxyphenyl hexopyranoside
4-{[(3R,4R)-4-(3,4-Dimethoxybenzyl)-2-oxotetrahydrofuran-3-yl]methyl}-2-methoxyphenyl beta-D-glucopyranoside
2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]-3-[[4-(-D-GLUCOPYRANOSYLOXY)-3-METHOXYPHENYL]METHYL]DIHYDRO-, (3R,4R)-
2(3H)-Furanone, 4-[(3,4-dimethoxyphenyl)methyl]-3-[[4-(b-D-glucopyranosyloxy)-3-methoxyphenyl]methyl]dihydro-, (3R,4R)-
2(3H)-furanone, 4-[(3,4-dimethoxyphenyl)methyl]-3-[[4-(beta-D-glucopyranosyloxy)-3-methoxyphenyl]methyl]dihydro-, (3R,4R)-
2 (3H)-Furanone, 4-[(3, 4-dimethoxyphenyl)methyl]-3-[[4-(.beta.-D-gluc opyranosyloxy)-3-met hoxyphenyl]methyl]dihydro-, (3R-trans)-
CAS20362-31-6
EINECS
Chemical FormulaC27H34O11
Molecular Weight534.55
inchiInChI=1/C27H34O11/c1-33-18-6-4-14(10-20(18)34-2)8-16-13-36-26(32)17(16)9-15-5-7-19(21(11-15)35-3)37-27-25(31)24(30)23(29)22(12-28)38-27/h4-7,10-11,16-17,22-25,27-31H,8-9,12-13H2,1-3H3/t16-,17+,22?,23?,24?,25?,27?/m0/s1
Package10 mM * 1 mL;50 mg;100 mg
PriceEmail to quote
DescriptionsArctiin

Arctiin

MedChemExpress (MCE)

HY-N0034

20362-31-6

Arctii

Descriptions

Arctiin

Arctiin

MedChemExpress (MCE)

HY-N0034

20362-31-6

Arctii
NSC 315527
Arctigenin-4-glucoside

99.92%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year

Room temperature in continental US
may vary elsewhere.

Arctiin is an orally active inhibitor of NF-κB. Arctiin suppresses cyclin D1 protein expression in human tumor cells. Arctiin also reduces malondialdehyde and pro-inflammatory cytokines levels. Arctiin can used in study glomerulonephritis.

Arctiin (100 µM) down-regulates cyclin D1 protein expression in human tumor cells[6].

Arctiin (120 mg/kg for p.o.
Once daily for 3 weeks) significantly improves cBSA-induced glomerulonephritis in glomerulonephritis rat model[4].

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[1]. Huang DM, et al. Modulation of anti-adhesion molecule MUC-1 is associated with arctiin-induced growth inhibition in PC-3 cells. Prostate. 2004 May 15
59(3):260-7.
[Content Brief]

[2]. Knipping K, et al. In vitro and in vivo anti-allergic effects of Arctium lappa L. Exp Biol Med (Maywood). 2008 Nov
233(11):1469-77.
[Content Brief]

[3]. Zeng Y, et al. Lack of significant modifying effect of arctiin on prostate carcinogenesis in probasin/SV40 T antigen transgenic rats. Cancer Lett. 2005 May 26
222(2):145-51.
[Content Brief]

[4]. Wu JG, et al. Ameliorative effects of arctiin from Arctium lappa on experimental glomerulonephritis in rats. Phytomedicine. 2009 Nov
16(11):1033-41.
[Content Brief]

[5]. Ma ST, et al. Effect of arctiin on glomerular filtration barrier damage in STZ-induced diabetic nephropathy rats. Phytother Res. 2013 Oct
27(10):1474-80.
[Content Brief]

[6]. Matsuzaki Y, et al. Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression. Oncol Rep. 2008 Mar
19(3):721-7.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/Arctiin.html
Last Update2025-05-21 16:50:25
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