2-Amino-2-methyl-1-propanol2-Amino-2-methyl-1-propanol
MedChemExpress (MCE)
HY-W013027
124-68-5
99.83%
4°C, protect from light *In solvent : -80°C, 6 months
-20°C, 1 month (protect from light)
Room temperature in continental US
may vary elsewhere.
2-Amino-2-methyl-1-propanol (AMP) is a neutralizer, buffer and surfactant. 2-Amino-2-methyl-1-propanol inhibits gelatinous product formation. 2-Amino-2-methyl-1-propanol is used for carbon dioxide absorption.
2-Amino-2-methyl-1-propanol (170-350 mM) is used for histochemical demonstration of alkaline phosphatase activity[2]. 2-Amino-2-methyl-1-propanol is used for carbon dioxide absorption[3]. 2-Amino-2-methyl-1-propanol inhibits gelatinous product formation in non-aqueous CO2 absorbents[4].
2-Amino-2-methyl-1-propanol (300-380 mg/kg, dermal exposure) does not cause liver effects in rats[5]. 2-Amino-2-methyl-1-propanol (0-600 ppm, p.o., 8 weeks) shows no compound-related changes in mice[5]. 2-Amino-2-methyl-1-propanol (1100-1700 mg/kg, p.o., 30 days) shows elevated SGPT and OCT serum levels in some of the rats, but there are no accompanying gross pathology or histopathology changes[5].
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[1]. Hong NS, et al. Rapid and accurate determination of deoxyribonucleoside monophosphates from DNA using micellar electrokinetic chromatography with a cationic surfactant additive. Anal Bioanal Chem. 2011 Jun
400(7):2131-40. [Content Brief]
[2]. SHI Y U X I U, et al. Use of AMP (2-amino-2-methyl-1-propanol) buffer for histochemical demonstration of alkaline phosphatase activity. Acta histochemica et cytochemica, 1988, 21(4): 321-326.
[3]. Zhang P, et al. Regeneration of 2-amino-2-methyl-1-propanol used for carbon dioxide absorption. J Environ Sci (China). 2008
20(1):39-44. [Content Brief]
[4]. Liu C, et al. Inhibiting effect of 2-amino-2-methyl-1-propanol on gelatinous product formation in non-aqueous CO2 absorbents: experimental study and molecular understanding. Chemical Engineering Journal, 2024, 481: 148545.
[5]. Garnick L, et al. Dose and exposure route analyses inform relationships between liver steatosis and 2-amino-2-methyl-1-propanol: Implications for hazard characterization. J Appl Toxicol. 2022 Dec
42(12):1873-1889. [Content Brief]