Fucosterol MedChemExpress (MCE)

Product Name	FUCOSTEROL
Synonyms	FUCOSTEROL trans-24-Ethylidenecholesterol 5,24[28]-STIGMASTADIEN-3BETA-OL 24-ETHYLIDENCHOLEST-5-ENE-3BETA-OL 3BETA-HYDROXY-5,24[28]-STIGMASTADIENE 5-CHOLESTEN-24(28)-ETHYLIDENE-3-BETA-OL Synonyms FUCOSTEROL trans-24-Ethylidenecholesterol 5,24[28]-STIGMASTADIEN-3BETA-OL 24-ETHYLIDENCHOLEST-5-ENE-3BETA-OL 3BETA-HYDROXY-5,24[28]-STIGMASTADIENE 5-CHOLESTEN-24(28)-ETHYLIDENE-3-BETA-OL 5,24(28)E-CHOLESTADIEN-24-ETHYL-3BETA-OL Stigmasta-5,24(28)-dien-3-ol, (3beta,24E)-
CAS	17605-67-3
EINECS
Chemical Formula	C29H48O
Molecular Weight	412.69
inchi
Package	10 mM * 1 mL;1 mg;5 mg;10 mg;20 mg
Price	Email to quote
Descriptions	Fucosterol Fucosterol MedChemExpress (MCE) HY-N4103 17605-67-3 98.27% 4°C, protect from light In solvent : -80°C, 6 months Descriptions Fucosterol Fucosterol MedChemExpress (MCE) HY-N4103 17605-67-3 98.27% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. Fucosterol is a sterol isolated from algae, seaweed or diatoms. Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities. Fucosterol regulates adipogenesis via inhibition of PPARα and C/EBPα expression and can be used for anti-obesity agents development research. Fucosterol (0-50 μM 7 days) suppresses the expression of PPARα and C/EBPα when compared to fully differentiated control adipocytes[1]. Fucosterol shows cytotoxicity against T47D and HT29 cell lines with IC50 values of 27.94 and 70.41 μg/ml, respectively[3].Fucosterol decreases cell HEK293, MCF-7, and SiHa cells proliferation with IC50 values of 185.4, 43.3, and 34.0 μg/ml, respectively[4]. Fucosterol (oral adminstratin 30mg/kg) causes a significant decrease in serum glucose concentrations, and exhibits an inhibition of sorbitol accumulations in the lenses[2]. PPARα C/EBPα[1] In Vitro Fucosterol (0-50 μM 7 days) suppresses the expression of PPARα and C/EBPα when compared to fully differentiated control adipocytes[1]. Fucosterol shows cytotoxicity against T47D and HT29 cell lines with IC50 values of 27.94 and 70.41 μg/ml, respectively[3].Fucosterol decreases cell HEK293, MCF-7, and SiHa cells proliferation with IC50 values of 185.4, 43.3, and 34.0 μg/ml, respectively[4]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Fucosterol Related Antibodies Cell Viability Assay[1] Cell Line: 3T3-L1 adipocytes \| \| \| \| \| \| \| \| \| \| [1]. Jung HA, et al. Anti-adipogenic activity of the edible brown alga Ecklonia stolonifera and its constituent fucosterol in 3T3-L1 adipocytes. Arch Pharm Res. 2014 Jun 37(6):713-20. [Content Brief] [2]. Lee YS, et al. Anti-diabetic activities of fucosterol from Pelvetia siliquosa. Arch Pharm Res. 2004 Nov 27(11):1120-2. [Content Brief] [3]. Qudeer Ahmed Abdul, et al. Health benefit of fucosterol from marine algae: a review. J Sci Food Agric. 2016 Apr 96(6):1856-66 [Content Brief] [4]. Khanavi M, et al. Cytotoxicity of fucosterol containing fraction of marine algae against breast and colon carcinoma cell line. Pharmacogn Mag. 2012 Jan 8(29):60-4. [Content Brief] [5]. Caamal-Fuentes E, et al. Cytotoxic and antiproliferative constituents from Dictyota ciliolata, Padina sanctae-crucis and Turbinaria tricostata. Pharm Biol. 2014 Oct 52(10):1244-8. [Content Brief]
Last Update	2025-04-01 14:45:47

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