Golotimod MedChemExpress (MCE)

Product Name	Golotimod (SCV-07)
Synonyms	GLU-TRP;GAMMA-GLU-TRP;Unii-637C487Y09;H-g-D-Glu-Trp-OH;gamma-D-Glu-L-Trp;Golotimod (SCV-07);H-D-GLU(TRP-OH)-OH;H-GAMMA-GLU-TRP-OH;H-GAMMA-D-GLU-TRP-OH
CAS	229305-39-9
EINECS
Chemical Formula	C16H19N3O5
Molecular Weight	333.34
inchi
Package	1 mg;5 mg;10 mg;25 mg;50 mg;100 mg
Price	Get quote
Descriptions	Golotimod Golotimod MedChemExpress (MCE) HY-14743 229305-39-9 SCV 07 Descriptions Golotimod Golotimod MedChemExpress (MCE) HY-14743 229305-39-9 SCV 07 Gamma-D-glutamyl-L-tryptophan 98.04% -20°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture and light) Room temperature in continental US may vary elsewhere. Golotimod (SCV-07), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod (SCV-07) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod (SCV-07) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2). Golotimod (SCV-07) (oral gavage or subcutaneous injection, 100 μg/kg, 5 days) reduces experimental recurrent genital HSV-2 disease by oral administration, more importantly, oral SCV07 after fasting shows a greater reduction in incidence and severity than SCV-07 without fasting in female hartley guinea pigs[1]. Golotimod (SCV-07) (subcutaneous injection, once or twice a day from days 1 to 20, 100 μg/kg) can reduce the severity and duration of acute and split radiation-induced oral mucositis (OM) and short the duration of ulcerative OM in male LVG golden Syrian Hamsters[3]. STAT3 \| \| \| \| \| \| \| \| \| \| [1]. Rose WA 2nd, et al. An immunomodulating dipeptide, SCV-07, is a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2). Int J Antimicrob Agents. 2008 Sep 32(3):262-6. [Content Brief]* [2]. Geiger JL, et al. The STAT3 pathway as a therapeutic target in head and neck cancer: Barriers and innovations. Oral Oncol. 2016 May 56:84-92. [Content Brief] [3]. Watkins B, et al. Attenuation of radiation- and chemoradiation-induced mucositis using gamma-D-glutamyl-L-tryptophan (SCV-07). Oral Dis. 2010 Oct 16(7):655-60. [Content Brief]
Last Update	2025-04-01 14:45:47

MedChemExpress (MCE) also provides

Lysyllysine dihydrochloride

Category: Peptides
CAS: 52123-30-5
Last Update: 2025-04-01 14:45:47

Aureusimine B

Category: Peptides
CAS: 170713-71-0
Last Update: 2025-04-01 14:45:47

Cyclo(Pro-Val)

Category: Peptides
CAS: 5654-87-5
Last Update: 2025-04-01 14:45:47

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2

Category: Peptides
CAS: 720710-69-0
Last Update: 2025-04-01 14:45:47

N,S-Bis-Fmoc-Glutathione

Category: Peptides
CAS: 149438-56-2
Last Update: 2025-04-01 14:45:47

Phe-Pro-Ala-pNA

Category: Peptides
CAS: 201738-99-0
Last Update: 2025-04-01 14:45:47

Cyclo(-Leu-Phe)

Category: Peptides
CAS: 7280-77-5
Last Update: 2025-04-01 14:45:47

H-γ-Glu-Leu-OH

Category: Peptides
CAS: 2566-39-4
Last Update: 2025-04-01 14:45:47


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact