Name | Golotimod (SCV-07) |
Synonyms | GLU-TRP GAMMA-GLU-TRP Unii-637C487Y09 H-g-D-Glu-Trp-OH gamma-D-Glu-L-Trp Golotimod (SCV-07) H-D-GLU(TRP-OH)-OH H-GAMMA-GLU-TRP-OH H-GAMMA-D-GLU-TRP-OH |
CAS | 229305-39-9 |
Molecular Formula | C16H19N3O5 |
Molar Mass | 333.34 |
Density | 1.428±0.06 g/cm3(Predicted) |
Boling Point | 737.3±60.0 °C(Predicted) |
pKa | 2.22±0.10(Predicted) |
Storage Condition | −20°C |
Use | Golotimod (SCV-07), an immunomodulatory peptide with antibacterial activity, can significantly improve the efficacy of anti-tuberculosis therapy, stimulate proliferation of thymus and spleen cells, and improve macrophage function. Golotimod (SCV-07) inhibits STAT3 signaling |
WGK Germany | 3 |
biological activity | Golotimod (SCV 07) an immunomodulatory peptide with antibacterial activity, can significantly improve the efficacy of anti tuberculosis research, stimulate thymus and spleen cell proliferation, and improve macrophage function. Golotimod inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models receiving radiotherapy or radiotherapy in combination with cisplatin. Golotimod has potential for the Study of recurrent genital Herpes Sinplex Virus type 2 (HSV-2). |
Target | STAT3 |