103-74-2
2-(2-Hydroxyethyl)pyridine
CAS: 103-74-2
Molecular Formula: C7H9NO
103-74-2 - Names and Identifiers
| Name | 2-(2-Hydroxyethyl)pyridine |
| Synonyms | 2-Pyridineethanol 2-(2-Pyridyl)ethanol 2-(pyridin-2-yl)ethanol 2-(2-Hydroxyethyl)pyridine |
| CAS | 103-74-2 |
| EINECS | 203-140-2 |
| InChI | InChI=1/C7H9NO/c9-6-4-7-3-1-2-5-8-7/h1-3,5,9H,4,6H2 |
103-74-2 - Physico-chemical Properties
| Molecular Formula | C7H9NO |
| Molar Mass | 123.152 |
| Density | 1.09g/cm3 |
| Melting Point | -8--7°C |
| Boling Point | 240.6°C at 760 mmHg |
| Flash Point | 92.8°C |
| Water Solubility | soluble |
| Vapor Presure | 0.0204mmHg at 25°C |
| Appearance | Morphological Liquid |
| Color | Clear yellow to brown |
| BRN | 111205 |
| pKa | 14.49±0.10(Predicted) |
| PH | 8-9 (100g/l, H2O, 20℃) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Sensitive | Hygroscopic |
| Refractive Index | 1.539 |
| Physical and Chemical Properties | Chemical Properties The product has a boiling point of 114-116 ℃(1.2kPa), a relative density of 1.093, a refractive index of 1.5368, and a flash point of 92 ℃. |
| Use | Use 2-hydroxyethyl pyridine is a metabolite of the anti-vertigo drug betahistine. |
103-74-2 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 2 |
| RTECS | UT2970450 |
| FLUKA BRAND F CODES | 3 |
| TSCA | Yes |
| HS Code | 29333999 |
103-74-2 - Upstream Downstream Industry
| Downstream Products | Betahistine 2-Vinylpyridine 2-Piperidineethanol 2-(2-BROMO-ETHYL)-PYRIDINE HYDROBROMIDE 2-Picolinic acid |
103-74-2 - Nature
| Solubility | Soluble in Chloroform (Slightly), Methanol (Slightly). |
| NIST chemical information | 2-Pyridineethanol(103-74-2) |
| EPA chemical information | 2-Pyridineethanol (103-74-2) |
Last Update：2024-04-10 22:29:15
103-74-2 - Production method
It is obtained by the addition reaction of 2-methylpyridine and formaldehyde. Formaldehyde and 2-methylpyridine are added into the reaction pot, nitrogen is introduced, stirred and heated to 125 ℃ at a pressure of about 0.4MPa, and after 20h of reaction, vacuum distillation is carried out to collect 130-145 ℃(2.13kPa) fractions to obtain 2-(2-hydroxyethyl) pyridine.
Last Update：2024-04-10 22:29:15
103-74-2 - Security information
| toxic substance data | 103-74-2(Hazardous Substances Data) |
Last Update：2024-04-10 22:29:15
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View History
Downstream Products for 103-74-2
Betahistine
2-Vinylpyridine
2-Piperidineethanol
2-(2-BROMO-ETHYL)-PYRIDINE HYDROBROMIDE
2-Picolinic acid
2-Vinylpyridine
2-Piperidineethanol
2-(2-BROMO-ETHYL)-PYRIDINE HYDROBROMIDE
2-Picolinic acid