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10300-27-3

3'-O-Methyl-Guanosine

CAS: 10300-27-3

Molecular Formula: C11H15N5O5

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10300-27-3 - Names and Identifiers

Name 3'-O-Methyl-Guanosine
Synonyms 3-OMG
3'-OMe-G
3'-O-Me-Gr
NSC 106541
3'-O-Methylguanosine
3'-O-Methyl-Guanosine
Guanosine, 3'-O-methyl-
3'-O-methylguanosine top3
2-amino-9-(3-O-methylpentofuranosyl)-3,9-dihydro-6H-purin-6-one
2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]-3H-purin-6-one
2-amino-9-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxy methyl)-4-methoxy tetra hydrofuran-2-yl)-1H-purin-6(9H)-one
CAS 10300-27-3
InChI InChI=1/C11H15N5O5/c1-20-7-4(2-17)21-10(6(7)18)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)

10300-27-3 - Physico-chemical Properties

Molecular FormulaC11H15N5O5
Molar Mass297.27
Density1.98±0.1 g/cm3(Predicted)
Melting Point263-300 °C (decomp)
Boling Point711.7°C at 760 mmHg
Flash Point384.2°C
Vapor Presure2.93E-21mmHg at 25°C
pKa9?+-.0.20(Predicted)
Storage ConditionRoom Temprature
Refractive Index1.829

10300-27-3 - Introduction

3 '-Methoxyguanosine (3'-Methylguanosine) is a nucleoside whose chemical formula is C11H15N5O5. It is the product of the reaction of the 3 '-hydroxyl site of guanosine with methanol. The following is a description of the properties, uses, preparation and safety information of 3 '-methoxyguanosine:

Nature:
-Appearance: White or almost white crystalline powder.
-Solubility: Soluble in water and methanol.

Use:
-Biochemistry: 3 '-Methoxyguanosine is commonly used to study the structure and function of RNA.
-Antiviral drug development: 3 '-methoxyguanosine has potential use in the development of antiviral drugs.

Preparation Method:
-A common preparation method is to obtain 3 '-methoxyguanosine by reacting guanosine with methanol under alkaline conditions.

Safety Information:
There is no clear information on the toxicity and danger of -3 '-methoxyguanosine, but as a chemical substance, attention should be paid to follow laboratory safety procedures.
-When handling 3 '-methoxyguanosine, it is recommended to wear suitable personal protective equipment, such as gloves, goggles, etc., to avoid direct contact or inhalation.
-Avoid exposing 3 '-methoxyguanosine to high temperatures, fire sources, or strong oxidants to prevent fire or explosion.
-Waste should be disposed of in accordance with local regulations.
Last Update:2024-04-09 15:17:50
10300-27-3
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