103030-28-0
6-BROMO-4-HYDROXY-2-METHYLQUINOLINE
CAS: 103030-28-0
Molecular Formula: C10H8BrNO
103030-28-0 - Names and Identifiers
| Name | 6-BROMO-4-HYDROXY-2-METHYLQUINOLINE |
| Synonyms | Ux00004208 6-BROMO-2-METHYL-4-QUINOLINOL 6-bromo-2-methylquinolin-4-ol 6-BROMO-2-METHYLQUINOLIN-4-OL 4-Quinolinol, 6-bromo-2-methyl- 6-bromo-2-methylquinolin-4(1H)-one 2-Methyl-4-hydroxy-6-broMoquinoline 6-BROMO-4-HYDROXY-2-METHYLQUINOLINE |
| CAS | 103030-28-0 |
| InChI | InChI=1/C10H8BrNO/c1-6-4-10(13)8-5-7(11)2-3-9(8)12-6/h2-5H,1H3,(H,12,13) |
103030-28-0 - Physico-chemical Properties
| Molecular Formula | C10H8BrNO |
| Molar Mass | 238.08 |
| Density | 1.612±0.06 g/cm3(Predicted) |
| Melting Point | 338 °C |
| Boling Point | 368.8±37.0 °C(Predicted) |
| Flash Point | 152.3°C |
| Vapor Presure | 0.000192mmHg at 25°C |
| pKa | 3.98±0.40(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.606 |
103030-28-0 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
103030-28-0 - Introduction
6-Bromo-2-methyl-4-hydroxyquinoline, also known as bromomethoquinoline, is an organic compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: 6-Bromo-2-methyl-4-hydroxyquinoline is a colorless or light yellow solid.
-Solubility: It is soluble in alcohol and ether solvents, insoluble in water.
-Stability: relatively stable at room temperature.
Use:
-Pharmaceutical field: 6-Bromo-2-methyl-4-hydroxyquinoline is an important intermediate compound that can be used to synthesize a variety of drugs, such as antimalarial drugs.
-Pesticide field: It can also be used as a pesticide intermediate.
Preparation Method:
6-bromo -2-methyl -4-hydroxyquinoline preparation method more, commonly used methods include:
1.6-bromo -2-methyl -4-hydroxyquinoline was obtained by ozone oxidation of methyl quinoline.
2. by the presence of sodium hydroxide in the methyl quinoline and bromine reaction system.
Safety Information:
-6-bromo-2-methyl-4-hydroxyquinoline has no obvious toxicity under general conditions, but it is still necessary to pay attention to safe operation.
-Wear chemical protective gloves and goggles during operation to avoid direct contact with skin and eyes.
-It should be operated in a well-ventilated place to avoid inhaling its dust or vapor.
-Should be stored in a dry, cool place, away from fire and oxidizing agents.
Nature:
-Appearance: 6-Bromo-2-methyl-4-hydroxyquinoline is a colorless or light yellow solid.
-Solubility: It is soluble in alcohol and ether solvents, insoluble in water.
-Stability: relatively stable at room temperature.
Use:
-Pharmaceutical field: 6-Bromo-2-methyl-4-hydroxyquinoline is an important intermediate compound that can be used to synthesize a variety of drugs, such as antimalarial drugs.
-Pesticide field: It can also be used as a pesticide intermediate.
Preparation Method:
6-bromo -2-methyl -4-hydroxyquinoline preparation method more, commonly used methods include:
1.6-bromo -2-methyl -4-hydroxyquinoline was obtained by ozone oxidation of methyl quinoline.
2. by the presence of sodium hydroxide in the methyl quinoline and bromine reaction system.
Safety Information:
-6-bromo-2-methyl-4-hydroxyquinoline has no obvious toxicity under general conditions, but it is still necessary to pay attention to safe operation.
-Wear chemical protective gloves and goggles during operation to avoid direct contact with skin and eyes.
-It should be operated in a well-ventilated place to avoid inhaling its dust or vapor.
-Should be stored in a dry, cool place, away from fire and oxidizing agents.
Last Update：2024-04-09 02:00:40
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