1068155-43-0
2-Hydroxy-4-methoxyphenylboronic acid
CAS: 1068155-43-0
Molecular Formula: C7H9BO4
1068155-43-0 - Names and Identifiers
| Name | 2-Hydroxy-4-methoxyphenylboronic acid |
| Synonyms | 2-hydroxy-4-Methoxyphenylboronic acid 2-Hydroxy-4-methoxyphenylboronic acid Boronic acid, B-(2-hydroxy-4-methoxyphenyl)- |
| CAS | 1068155-43-0 |
1068155-43-0 - Physico-chemical Properties
| Molecular Formula | C7H9BO4 |
| Molar Mass | 167.96 |
| Storage Condition | 2-8 ℃, stored in nitrogen |
1068155-43-0 - Introduction
2-Hydroxy-4-methoxybenzeneboronic acid (acid) is an organic compound with the chemical formula C7H9BO4. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystal or crystalline powder
-Melting point: 197-202°C
-Solubility: Soluble in common organic solvents, such as ethanol, dimethylformamide, etc.
-Stability: stable at room temperature, but avoid prolonged exposure to sunlight or high temperature environment
Use:
-Coordination reagent: As a reagent in the synthesis of metal complexes, it can form coordination compounds with metal ions, such as iron, zinc, etc.
-Organic synthesis: Widely used in the phenylboronic acid strategy, it can effectively synthesize organic molecules with multiple structures and functions through cross-coupling reactions similar to Suzuki-Miyaura reactions
-Pharmaceutical intermediates: As intermediates in drug development, it can be used to synthesize potential drug candidate compounds
Preparation Method:
-Usually prepared by the substitution reaction of hydroxyl and methoxy on phenylboronic acid. For example, phenylboronic acid is reacted with 2-hydroxy-4-methoxyphenyl lithium to produce 2-hydroxy-4-methoxyphenylboronic acid.
Safety Information:
-2-Hydroxy-4-methoxybenzene boronic acid is not significantly hazardous under normal conditions of use.
-But avoid its reaction with strong oxidants to prevent fire or explosion.
-And should be used correctly in accordance with laboratory safety practices, and wear appropriate personal protective equipment, such as laboratory gloves, safety glasses, etc.
Nature:
-Appearance: White crystal or crystalline powder
-Melting point: 197-202°C
-Solubility: Soluble in common organic solvents, such as ethanol, dimethylformamide, etc.
-Stability: stable at room temperature, but avoid prolonged exposure to sunlight or high temperature environment
Use:
-Coordination reagent: As a reagent in the synthesis of metal complexes, it can form coordination compounds with metal ions, such as iron, zinc, etc.
-Organic synthesis: Widely used in the phenylboronic acid strategy, it can effectively synthesize organic molecules with multiple structures and functions through cross-coupling reactions similar to Suzuki-Miyaura reactions
-Pharmaceutical intermediates: As intermediates in drug development, it can be used to synthesize potential drug candidate compounds
Preparation Method:
-Usually prepared by the substitution reaction of hydroxyl and methoxy on phenylboronic acid. For example, phenylboronic acid is reacted with 2-hydroxy-4-methoxyphenyl lithium to produce 2-hydroxy-4-methoxyphenylboronic acid.
Safety Information:
-2-Hydroxy-4-methoxybenzene boronic acid is not significantly hazardous under normal conditions of use.
-But avoid its reaction with strong oxidants to prevent fire or explosion.
-And should be used correctly in accordance with laboratory safety practices, and wear appropriate personal protective equipment, such as laboratory gloves, safety glasses, etc.
Last Update：2024-04-09 02:00:41
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Tel: 400-968-2212
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Mobile: 18916960931
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CAS: 1068155-43-0
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CAS: 1068155-43-0
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