115104-28-4
(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT
CAS: 115104-28-4
Molecular Formula: C26H27ClN2O3S2
115104-28-4 - Names and Identifiers
115104-28-4 - Physico-chemical Properties
| Molecular Formula | C26H27ClN2O3S2 |
| Molar Mass | 515.09 |
| Density | 1.327±0.06 g/cm3(Predicted) |
| Melting Point | 65-70°C |
| Boling Point | 712.3±60.0 °C(Predicted) |
| Solubility | Soluble in DMSO (up to 50 mg/ml). |
| Appearance | Off-white solid. |
| Color | Yellow |
| pKa | 4.27±0.10(Predicted) |
| Storage Condition | Store at -20°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
| In vitro study | L-660,711(MK-571) inhibited the binding of [3H]LTD4 in guinea pig lung with a Ki value of 0.22±0.15 nM (n = 35), and inhibited the binding of [3H]LTD4 in human lung, the Ki value was 2.1±1.8 nM (n = 29). L660,711 had low or no activity against [3H]LTC4, and the IC50 in guinea pig lung was 23±11 μm (n = 16), the IC50 in human lung was 32 μm (n = 1). |
| In vivo study | MK-571 was well tolerated by healthy young adults. After oral administration, MK-571 is rapidly absorbed. The plasma concentration reached a peak after 1.1-1.5 hours after administration. |
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Product Name: (E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT Visit Supplier Webpage Request for quotation
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Product Name: (E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT Visit Supplier Webpage Request for quotation
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