119425-89-7
Loureirin A
CAS: 119425-89-7
Molecular Formula: C17H18O4
119425-89-7 - Names and Identifiers
119425-89-7 - Physico-chemical Properties
| Molecular Formula | C17H18O4 |
| Molar Mass | 286.32 |
| Density | 1.170 |
| Boling Point | 479.1±40.0 °C(Predicted) |
| Solubility | DMSO : ≥ 86.6 mg/mL (302.46 mM) |
| Appearance | Powder |
| pKa | 8.08±0.15(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD10566607 |
| Physical and Chemical Properties | White crystal, soluble in methanol, ethanol, DMSO and other organic solvents, from the dragon blood scorpion. |
| In vitro study | Loureirin A (50 μM, 100 μM) inhibits collagen-induced platelet ATP secretion and thrombin-stimulated P-selectin expression in a dose-dependent manner. Loureirin A also significantly impairs platelet spreading on immobilized fibrinogen. Loureirin A almost completely eliminates collagen-induced Akt phosphorylation at Ser473 at the dose of 100 μM, and has an additive inhibitory effect with the phosphoinositide 3-kinase (PI3K) inhibitor Ly294002 on collage-induced Akt phosphorylation in platelets at 50 μM. |
119425-89-7 - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29145090 |
119425-89-7 - Reference
| Reference Show more | 1. [IF=5.923] Yujuan Li et al."Dragon’s Blood Regulates Rac1-WAVE2-Arp2/3 Signaling Pathway to Protect Rat Intestinal Epithelial Barrier Dysfunction Induced by Simulated Microgravity."Int J Mol Sci. 2021 Jan;22(5):2722 |
119425-89-7 - Introduction
Loureirin A is A unique substance naturally produced in dracaena, also known as sabergen X(S-Mirokolixin). The following is A description of the nature, use, formulation and safety information of Loureirin A:
Nature:
- Loureirin A is A red resinous substance with remarkable antioxidant and anti-inflammatory properties.
-Its chemical structure is complex, mainly composed of monoterpenoids and polyesters.
Use:
- Loureirin A is widely used in the pharmaceutical and cosmetic industries.
-In the field of medicine, Loureirin A has been found to have anti-tumor, anti-virus, antibacterial and immunomodulatory activities, so it has potential application prospects in tumor treatment and immune enhancement.
-In the field of cosmetics, Loureirin A is often used for anti-aging and anti-wrinkle, and has the effect of promoting collagen synthesis and protecting the skin from free radical damage.
Preparation Method:
- Loureirin A preparation method usually involves the extraction and separation of purified substances from Dracaena.
-The most commonly used methods include ultrasonic extraction, immersion and solvent separation.
Safety Information:
- Loureirin A is considered A relatively safe natural substance, but should follow appropriate dosage and application guidelines.
-Although no significant side effects or toxicities have been reported, safety needs to be further studied in pregnant women, lactating women, and children.
-When using Loureirin A cosmetics, it is recommended to perform A sensitivity test to ensure that there is no allergic reaction or irritation.
-As an emerging Drug and Cosmetic ingredient, the safety and effectiveness of Loureirin A still needs further scientific research and evaluation.
Nature:
- Loureirin A is A red resinous substance with remarkable antioxidant and anti-inflammatory properties.
-Its chemical structure is complex, mainly composed of monoterpenoids and polyesters.
Use:
- Loureirin A is widely used in the pharmaceutical and cosmetic industries.
-In the field of medicine, Loureirin A has been found to have anti-tumor, anti-virus, antibacterial and immunomodulatory activities, so it has potential application prospects in tumor treatment and immune enhancement.
-In the field of cosmetics, Loureirin A is often used for anti-aging and anti-wrinkle, and has the effect of promoting collagen synthesis and protecting the skin from free radical damage.
Preparation Method:
- Loureirin A preparation method usually involves the extraction and separation of purified substances from Dracaena.
-The most commonly used methods include ultrasonic extraction, immersion and solvent separation.
Safety Information:
- Loureirin A is considered A relatively safe natural substance, but should follow appropriate dosage and application guidelines.
-Although no significant side effects or toxicities have been reported, safety needs to be further studied in pregnant women, lactating women, and children.
-When using Loureirin A cosmetics, it is recommended to perform A sensitivity test to ensure that there is no allergic reaction or irritation.
-As an emerging Drug and Cosmetic ingredient, the safety and effectiveness of Loureirin A still needs further scientific research and evaluation.
Last Update：2024-04-09 01:59:57
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