121303-75-1
5-(difluoromethyl)-1-methyl-1H-pyrazol-3-ol
CAS: 121303-75-1
Molecular Formula: C5H6F2N2O
121303-75-1 - Names and Identifiers
121303-75-1 - Physico-chemical Properties
| Molecular Formula | C5H6F2N2O |
| Molar Mass | 148.11 |
121303-75-1 - Introduction
1-Methyl-3-hydroxy-5-difluoromethylpyrazole is an organic compound with the chemical formula C6H5F2N2O, which has the following properties:
1. Appearance: Colorless to light yellow crystal, soluble in ethanol and methanol, slightly soluble in water.
2. Melting point: about 96-100°C.
3. Stability: It is relatively stable at room temperature, but it is better to avoid light and moisture.
1-methyl -3-hydroxy -5-difluoromethylpyrazole has a wide range of applications in the field of chemistry and medicine:
1. pesticide: as an intermediate of pesticides and herbicides.
2. photosensitive materials: used for photochromic, photoresist and photosensitive resin synthesis.
3. medicine: as a drug synthesis intermediate, used in the synthesis of antiviral, antitumor and antibacterial drugs.
The method of preparing 1-methyl -3-hydroxy -5-difluoromethylpyrazole is generally through the following steps:
1. react 1-pyrazole ketone with dichloromethane to generate 1-methyl pyrazole ketone.
2. react 1-methyl pyrazole ketone with hydrofluoric acid to generate 1-methyl -3-fluoromethyl pyrazole ketone.
3.1-methyl -3-fluoromethyl pyrazole ketone is reacted with sodium hydroxide or other bases to generate 1-methyl -3-hydroxy -5-fluoromethyl pyrazole.
4.1-methyl -3-hydroxy -5-fluoromethylpyrazole is reacted with dichloromethane and a base to generate 1-methyl -3-hydroxy -5-difluoromethylpyrazole.
Regarding safety information, 1-methyl-3-hydroxy-5-difluoromethylpyrazole is an organic compound that is dangerous and requires the following safety precautions:
1. Avoid contact with skin, eyes and respiratory tract. In case of contact, rinse immediately with plenty of water and seek medical treatment.
2. Personal protective equipment such as lab gloves, goggles and protective masks should be worn during use.
3. should be used in a well-ventilated place to operate, avoid inhalation of gas, steam or dust.
4. storage should be away from fire, heat and oxidant, avoid direct sunlight.
5. Waste disposal shall comply with local environmental regulations.
Before using or contacting 1-methyl-3-hydroxy-5-difluoromethylpyrazole, it is recommended to learn more about its safe operation and use, and wear appropriate personal protective equipment.
1. Appearance: Colorless to light yellow crystal, soluble in ethanol and methanol, slightly soluble in water.
2. Melting point: about 96-100°C.
3. Stability: It is relatively stable at room temperature, but it is better to avoid light and moisture.
1-methyl -3-hydroxy -5-difluoromethylpyrazole has a wide range of applications in the field of chemistry and medicine:
1. pesticide: as an intermediate of pesticides and herbicides.
2. photosensitive materials: used for photochromic, photoresist and photosensitive resin synthesis.
3. medicine: as a drug synthesis intermediate, used in the synthesis of antiviral, antitumor and antibacterial drugs.
The method of preparing 1-methyl -3-hydroxy -5-difluoromethylpyrazole is generally through the following steps:
1. react 1-pyrazole ketone with dichloromethane to generate 1-methyl pyrazole ketone.
2. react 1-methyl pyrazole ketone with hydrofluoric acid to generate 1-methyl -3-fluoromethyl pyrazole ketone.
3.1-methyl -3-fluoromethyl pyrazole ketone is reacted with sodium hydroxide or other bases to generate 1-methyl -3-hydroxy -5-fluoromethyl pyrazole.
4.1-methyl -3-hydroxy -5-fluoromethylpyrazole is reacted with dichloromethane and a base to generate 1-methyl -3-hydroxy -5-difluoromethylpyrazole.
Regarding safety information, 1-methyl-3-hydroxy-5-difluoromethylpyrazole is an organic compound that is dangerous and requires the following safety precautions:
1. Avoid contact with skin, eyes and respiratory tract. In case of contact, rinse immediately with plenty of water and seek medical treatment.
2. Personal protective equipment such as lab gloves, goggles and protective masks should be worn during use.
3. should be used in a well-ventilated place to operate, avoid inhalation of gas, steam or dust.
4. storage should be away from fire, heat and oxidant, avoid direct sunlight.
5. Waste disposal shall comply with local environmental regulations.
Before using or contacting 1-methyl-3-hydroxy-5-difluoromethylpyrazole, it is recommended to learn more about its safe operation and use, and wear appropriate personal protective equipment.
Last Update：2024-04-09 20:02:46
Supplier List
Spot supply
Product Name: 5-(difluoromethyl)-1-methyl-1H-pyrazol-3-ol Request for quotationCAS: 121303-75-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 5-Difluoromethyl-1-methyl-1H-pyrazol-3-ol Visit Supplier Webpage Request for quotationCAS: 121303-75-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 5-(difluoromethyl)-1-methyl-1H-pyrazol-3-ol Visit Supplier Webpage Request for quotationCAS: 121303-75-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 5-Difluoromethyl-1-methyl-1H-pyrazol-3-ol Visit Supplier Webpage Request for quotationCAS: 121303-75-1
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 5-(difluoromethyl)-1-methyl-1H-pyrazol-3-ol Request for quotationCAS: 121303-75-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 5-Difluoromethyl-1-methyl-1H-pyrazol-3-ol Visit Supplier Webpage Request for quotationCAS: 121303-75-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 5-(difluoromethyl)-1-methyl-1H-pyrazol-3-ol Visit Supplier Webpage Request for quotationCAS: 121303-75-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 5-Difluoromethyl-1-methyl-1H-pyrazol-3-ol Visit Supplier Webpage Request for quotationCAS: 121303-75-1
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
View History