132-17-2
benztropine mesylate
CAS: 132-17-2
Molecular Formula: C22H29NO4S
132-17-2 - Names and Identifiers
| Name | benztropine mesylate |
| Synonyms | benztropine mesylate benzatropine mesilate BENZTROPINEMESYLATE,USP Benztropine mesylate salt benztropine methane sulfonate Benztropine Mesylate (200 mg) Benztropine methanesulfonate salt 3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane sulfate 1.alpha.H,5.alpha.H-Tropane, 3.alpha.-(diphenylmethoxy)-, methanesulfonate 8-Azabicyclo[3.2.1]octane, 3-(diphenylmethoxy)-8-methyl-, endo-, methanesulfonate 8-Azabicyclo3.2.1octane, 3-(diphenylmethoxy)-8-methyl-, (3-endo)-, methanesulfonate |
| CAS | 132-17-2 |
| EINECS | 205-048-8 |
| InChI | InChI=1/C21H25NO.CH4O3S/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17;1-5(2,3)4/h2-11,18-21H,12-15H2,1H3;1H3,(H,2,3,4)/t18-,19+,20+ |
132-17-2 - Physico-chemical Properties
| Molecular Formula | C22H29NO4S |
| Molar Mass | 403.53 |
| Melting Point | 135°C(lit.) |
| Boling Point | 547.8°C at 760 mmHg |
| Flash Point | 285.1°C |
| Water Solubility | Soluble in water (81 mg/ml at 25°C), DMSO (50 mg/ml at 25°C), ethanol (81 mg/ml at 25°C), and ether (very slightly). |
| Solubility | H2O: soluble20mg/mL, clear |
| Vapor Presure | 7.83E-13mmHg at 25°C |
| Appearance | powder |
| Color | white to beige |
| Storage Condition | Inert atmosphere,2-8°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
| In vitro study | Benztropine inhibits MTSET-induced [the apparent equilibrium dissociation constant of W84L DAT to Benztropine in the absence of sodium salt is significantly higher than that of wild-type DAT, and this difference is in [. |
| In vivo study | Benztropine (3.0 mg/day) can effectively improve the tremor and motor scores of patients in the unified rating scale of Parkinson's disease, and does not bring adverse reactions such as leukopenia. Benztropine (5 mg/kg and 25 mg/kg) can increase the extracellular dopamine content in rat striatum with dose-dependent characteristics. |
132-17-2 - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | 23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. |
| Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | YM3150000 |
| HS Code | 2939800000 |
| Hazard Class | 6.1 |
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Product Name: Benzatropine mesylate (Standard); Benzotropine mesylate (Standard); Benztropine methanesulfonate (Standard) Visit Supplier Webpage Request for quotationCAS: 132-17-2
Tel: 609-228-6898
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View History
132-17-2
16732-73-3
4441-12-7
20261-38-5
118-52-5
Na2-S
Mikethrene Blue GCD
CARBOMER 934 (TECHNICAL GRADE)
2-Butanone,4-hydroxy-
sulfur dichloride
16732-73-3
4441-12-7
20261-38-5
118-52-5
Na2-S
Mikethrene Blue GCD
CARBOMER 934 (TECHNICAL GRADE)
2-Butanone,4-hydroxy-
sulfur dichloride