132812-72-7

132812-72-7 - Names and Identifiers

Name	4-(4-Fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2(1H)-one
Synonyms	4-(4-Fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin... 4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydro-1H-cyclooctapyridin-2-one 4-(4-Fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2(1H)-one 4-(4-Fluorophenyl)-5,6,7,8,9,10-hexahydro-1H-cycloocta[B]pyridin-2-one 4-(4-Fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-2(1H)-one Cycloocta[b]pyridin-2(1H)-one, 4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydro- (Z)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2(1H)-one
CAS	132812-72-7
InChI	InChI=1S/C17H18FNO/c18-13-9-7-12(8-10-13)15-11-17(20)19-16-6-4-2-1-3-5-14(15)16/h7-11H,1-6H2,(H,19,20)

132812-72-7 - Physico-chemical Properties

Molecular Formula	C17H18FNO
Molar Mass	271.33
Density	1.18
Melting Point	233-235°C
Boling Point	481.5±45.0 °C(Predicted)
Solubility	Chloroform (Slightly), Methanol (Slightly)
Appearance	Solid
Color	Pale Beige to Beige
pKa	12.71±0.40(Predicted)
Storage Condition	2-8°C

132812-72-7 - Introduction

4-(4-Fluorophenyl)-5,6,7,8, 9,10-hexahydrocyclooctano [B] pyridin -2(1H)-one, also known as F6BPK, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: F6BPK is a white solid.
-Melting point: The melting point of F6BPK is about 85-90°C.
-Molecular formula: C16H19FO.
-Molecular weight: The molecular weight of F6BPK is about 240.33g/mol.
-Solubility: F6BPK has good solubility in organic solvents.

Use:
- F6BPK is an important intermediate that can be used to synthesize various organic compounds, such as drugs, pesticides and dyes.
- F6BPK is widely used in the field of medicine, especially in the research and synthesis of anti-inflammatory and anti-tumor drugs.

Preparation Method:
-A common method for synthesizing F6BPK is obtained by fluorination of cyclooctane [B] pyrrole-2 (1H)-one. The specific preparation method is as follows:
1. First, cyclooctane [B] pyrrol-2 (1H)-one is added to an organic solvent together with reactants such as copper flouride (CuF) and ethyl iodide (CH3CH2I).
2. The reaction is carried out at an appropriate temperature and pressure.
3. The F6BPK product was obtained by crystallization and purification steps.

Safety Information:
-The safety of F6BPK has not been fully evaluated, so it must be used with caution.
-Wear appropriate protective equipment such as gloves, glasses and lab coats when handling F6BPK.
-Avoid inhalation, ingestion or contact with skin.
-When using F6BPK, it should be done in a well-ventilated area to avoid the accumulation of harmful gases.
-For specific chemical use and disposal recommendations, please refer to the relevant Safety Data Sheet (MSDS) or consult a professional. Be sure to know and follow the relevant safety procedures in advance.

Last Update：2024-04-09 21:01:54