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14001-63-9

4-Methyl-2-(Methylsulfanyl)Pyrimidine

CAS: 14001-63-9

Molecular Formula: C6H8N2S

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14001-63-9 - Names and Identifiers

Name 4-Methyl-2-(Methylsulfanyl)Pyrimidine
Synonyms 2-Methylthio-4-Methylpyrimidine
4-Methyl-2-Thiomethyl Pyrimidine
4-Methyl-2-(Methylthio)Pyrimidine
4-METHYL-2-(METHYLTHIO)PYRIMIDINE
Pyrimidine, 4-Methyl-2-(Methylthio)-
4-METHYL-2-(METHYLSULFANYL)PYRIMIDINE
Pyrimidine, 4-methyl-2-(methylthio)-
4-Methyl-2-(Methylsulfanyl)Pyrimidine
4-Methyl-2-(methylsulphanyl)pyrimidine
Pyrimidine, 4-methyl-2-(methylthio)- (6CI, 8CI, 9CI)
CAS 14001-63-9

14001-63-9 - Physico-chemical Properties

Molecular FormulaC6H8N2S
Molar Mass140.21
Density1.007 g/mL at 25 °C
Boling Point78-80°/1mm
Flash Point220°F
pKa1.35±0.20(Predicted)
Storage Condition2-8°C
Refractive Indexn20/D 1.572
Physical and Chemical PropertiesWGK Germany:3

14001-63-9 - Risk and Safety

Hazard SymbolsXn - Harmful
Harmful
Risk CodesR22 - Harmful if swallowed
R37/38 - Irritating to respiratory system and skin.
R41 - Risk of serious damage to eyes
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 - Wear eye / face protection.
WGK Germany3
HS Code29335990
Hazard ClassIRRITANT

14001-63-9 - Reference Information

Use 4-methyl-2-methylthiopyrimidine is a heterocyclic organic compound and can be used as a pharmaceutical intermediate.
preparation in argon atmosphere, to NaOH(7.46g,186.4mmol) water (120mL) solution
4-methylpyrimidine -2-thiol hydrochloride (13.78g,84.7mmol), then add
methyl iodide (13.23g,93.2mmol) dropwise. Stir at room temperature for 2 hours, then extract with CH2Cl2(2x)
. The organic phase is dried by Na2SO4 and concentrated to dryness. The crude product obtained was purified by silica gel chromatography, and a hexane-EtOAc mixture with increased polarity was used as an eluent to obtain
10.26g of the required compound (yield: 86%).
Last Update:2024-04-09 21:21:28
14001-63-9
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Jiangsu Pules Biotechnology Co.,Ltd.
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CAS: 14001-63-9
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
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Mobile: 18916960931
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