14631-46-0
5,6,7,8-Tetrahydroquinolin-8-ol
CAS: 14631-46-0
Molecular Formula: C9H11NO
14631-46-0 - Names and Identifiers
| Name | 5,6,7,8-Tetrahydroquinolin-8-ol |
| Synonyms | in-8-oL Tetrahydro-quinolin-8-ol 5,6,7,8-Tetrahydroquinolin-8-ol 5,6,7,8-tetrahydro-8-Quinolinol 5,6,7,8-Tetrahydroquinoline-8-ol 5,6,7,8-TETRAHYDRO-QUINOLIN-8-OL 8-quinolinol,5,6,7,8-tetrahydro- |
| CAS | 14631-46-0 |
| InChI | InChI=1/C9H11NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h2,4,6,8,11H,1,3,5H2 |
14631-46-0 - Physico-chemical Properties
| Molecular Formula | C9H11NO |
| Molar Mass | 149.19 |
| Density | 1.179±0.06 g/cm3(Predicted) |
| Melting Point | 64-65 °C |
| Boling Point | 88-96 °C(Press: 2 Torr) |
| Flash Point | 141°C |
| Vapor Presure | 0.000274mmHg at 25°C |
| pKa | 13.44±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.59 |
14631-46-0 - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | 25 - Toxic if swallowed |
| Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
14631-46-0 - Introduction
5,6, 7,8-tetrahydroquinolin-8-ol, also known as tetrahydroquinolin-8-ol, is an organic compound. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Usually colorless to light yellow crystals or crystalline powder.
-Solubility: Soluble in common solvents such as water, ethanol, benzene and chloroform.
-Melting point: About 102-105 ° C.
-molecular formula: C7H13NO.
-Molecular weight: 129.18g/mol.
Use:
-Pharmaceutical intermediates: 5,6, 7,8-tetrahydroquinolin-8-ol is commonly used as an intermediate in the synthesis of other active compounds in the pharmaceutical field.
-Biochemistry research: It is also used as a tool to study metabolic pathways and drug metabolism.
Method:
-Usually, 4-hydroxymorpholine can be reacted with bromoethane to generate 5-bromo-4-hydroxymorpholine, and then reacted with benzopyridine by heating and refluxing to generate 5-cyclobutene-1, 4-diketone derivatives. Finally, by treating this derivative with ammonia, 5,6, 7,8-tetrahydroquinolin-8-ol is produced.
Safety Information:
-There are few studies on the toxicity and danger of 5,6, 7,8-tetrahydroquinolin-8-ol, so it is necessary to pay attention to safe operation.
-When handling the compound, wear appropriate protective equipment, including laboratory gloves and protective glasses.
-Avoid inhalation, ingestion or skin contact to prevent accidental poisoning.
-During storage and handling, it should be kept separate from incompatible materials such as flammable materials and oxidants.
-Before use or disposal, it is recommended to consult the relevant safety data sheet for specific precautions for use and disposal.
Nature:
-Appearance: Usually colorless to light yellow crystals or crystalline powder.
-Solubility: Soluble in common solvents such as water, ethanol, benzene and chloroform.
-Melting point: About 102-105 ° C.
-molecular formula: C7H13NO.
-Molecular weight: 129.18g/mol.
Use:
-Pharmaceutical intermediates: 5,6, 7,8-tetrahydroquinolin-8-ol is commonly used as an intermediate in the synthesis of other active compounds in the pharmaceutical field.
-Biochemistry research: It is also used as a tool to study metabolic pathways and drug metabolism.
Method:
-Usually, 4-hydroxymorpholine can be reacted with bromoethane to generate 5-bromo-4-hydroxymorpholine, and then reacted with benzopyridine by heating and refluxing to generate 5-cyclobutene-1, 4-diketone derivatives. Finally, by treating this derivative with ammonia, 5,6, 7,8-tetrahydroquinolin-8-ol is produced.
Safety Information:
-There are few studies on the toxicity and danger of 5,6, 7,8-tetrahydroquinolin-8-ol, so it is necessary to pay attention to safe operation.
-When handling the compound, wear appropriate protective equipment, including laboratory gloves and protective glasses.
-Avoid inhalation, ingestion or skin contact to prevent accidental poisoning.
-During storage and handling, it should be kept separate from incompatible materials such as flammable materials and oxidants.
-Before use or disposal, it is recommended to consult the relevant safety data sheet for specific precautions for use and disposal.
Last Update：2024-04-09 21:00:56
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View History
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