154594-16-8
4H-1,2,4-Triazole,4-(4-hydrazinophenyl)-(9CI)
CAS: 154594-16-8
Molecular Formula: C8H9N5
154594-16-8 - Names and Identifiers
154594-16-8 - Physico-chemical Properties
| Molecular Formula | C8H9N5 |
| Molar Mass | 175.19 |
| Density | 1.39±0.1 g/cm3(Predicted) |
| Boling Point | 410.1±47.0 °C(Predicted) |
| Flash Point | 201.8°C |
| Vapor Presure | 6.16E-07mmHg at 25°C |
| pKa | 4.88±0.30(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.712 |
154594-16-8 - Introduction
4-(4-hydrazinophenyl)-1,2, 4-triazole hydrochloride, also known as hydrazinotriazole hydrochloride, its properties, uses, preparation and safety information are as follows:
Nature:
-Appearance: A colorless to light yellow crystalline solid.
-Solubility: Soluble in water and some organic solvents.
-Stability: relatively stable at room temperature and can be stored for a long time under dry conditions.
Use:
-Pharmaceutical field: Hydrazinotriazole hydrochloride is an important drug intermediate, which can be used to synthesize or prepare a variety of drugs, such as anti-cancer drugs.
-Pesticide field: Hydrazinotriazole hydrochloride can also be used as an intermediate for fungicides and plant growth regulators.
Method:
Hydrazinotriazole hydrochloride is typically synthesized by the following steps:
1. In glacial acetic acid to add hydrogen to sodium metal, and hydrazine reaction to form the sodium salt of hydrazine.
2. The sodium salt of hydrazine is reacted with 4-tert-butylbenzoyl chloride to generate 4-(4-hydrazinophenyl)-1,2, 4-triazole.
3. Finally, 4-(4-hydrazinophenyl)-1,2, 4-triazole was reacted with hydrochloric acid to obtain hydrazinotriazole hydrochloride.
Safety Information:
-Hydrazinotriazole hydrochloride has certain toxicity and irritation, should avoid inhalation, contact with skin and ingestion.
-Use should wear appropriate protective clothing and gloves to ensure a well-ventilated working environment.
-Avoid dust or splashing solution during operation to avoid respiratory tract, eye and skin irritation.
-In case of accidental contact, immediately flush the affected area with plenty of water and seek medical help.
Please note that this information is for reference only and that the safety data sheets and operating procedures for the relevant chemicals are also required for specific use.
Nature:
-Appearance: A colorless to light yellow crystalline solid.
-Solubility: Soluble in water and some organic solvents.
-Stability: relatively stable at room temperature and can be stored for a long time under dry conditions.
Use:
-Pharmaceutical field: Hydrazinotriazole hydrochloride is an important drug intermediate, which can be used to synthesize or prepare a variety of drugs, such as anti-cancer drugs.
-Pesticide field: Hydrazinotriazole hydrochloride can also be used as an intermediate for fungicides and plant growth regulators.
Method:
Hydrazinotriazole hydrochloride is typically synthesized by the following steps:
1. In glacial acetic acid to add hydrogen to sodium metal, and hydrazine reaction to form the sodium salt of hydrazine.
2. The sodium salt of hydrazine is reacted with 4-tert-butylbenzoyl chloride to generate 4-(4-hydrazinophenyl)-1,2, 4-triazole.
3. Finally, 4-(4-hydrazinophenyl)-1,2, 4-triazole was reacted with hydrochloric acid to obtain hydrazinotriazole hydrochloride.
Safety Information:
-Hydrazinotriazole hydrochloride has certain toxicity and irritation, should avoid inhalation, contact with skin and ingestion.
-Use should wear appropriate protective clothing and gloves to ensure a well-ventilated working environment.
-Avoid dust or splashing solution during operation to avoid respiratory tract, eye and skin irritation.
-In case of accidental contact, immediately flush the affected area with plenty of water and seek medical help.
Please note that this information is for reference only and that the safety data sheets and operating procedures for the relevant chemicals are also required for specific use.
Last Update：2024-04-09 21:00:56
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Product Name: 4-(4-Hydrazinylphenyl)-4H-1,2,4-triazole Request for quotationCAS: 154594-16-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Product Name: 4H-1,2,4-Triazole,4-(4-hydrazinophenyl)-(9CI) Visit Supplier Webpage Request for quotation
CAS: 154594-16-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 154594-16-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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