160194-29-6
4-(TRIETHYLSILYL)-3-BUTYN-1-OL
CAS: 160194-29-6
Molecular Formula: C10H20OSi
160194-29-6 - Names and Identifiers
| Name | 4-(TRIETHYLSILYL)-3-BUTYN-1-OL |
| Synonyms | TIMTEC-BB SBB009039 4-(TRIETHYLSILYL)-3-BUTYN-1-OL 4-(triethylsilyl)but-3-yn-1-ol 3-Butyn-1-ol, 4-(triethylsilyl)- |
| CAS | 160194-29-6 |
| InChI | InChI=1/C10H20OSi/c1-4-12(5-2,6-3)10-8-7-9-11/h11H,4-7,9H2,1-3H3 |
160194-29-6 - Physico-chemical Properties
| Molecular Formula | C10H20OSi |
| Molar Mass | 184.35 |
| Density | 0.877±0.06 g/cm3 (20 ºC 760 Torr) |
| Boling Point | 224.2±23.0℃ (760 Torr) |
| Flash Point | >63°C |
| Vapor Presure | 0.0187mmHg at 25°C |
| pKa | 14.46±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.4686 |
160194-29-6 - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
160194-29-6 - Introduction
4-(TRIETHYLSILYL)-3-BUTYN-1-OL is a pharmaceutical compound, commonly known as Adecainol, which contains Hydroxyethyl and Silyl groups in its chemical structure. The following is a description of its nature, use, formulation and safety information:
Nature:
Adecainol is a colorless to slightly yellow liquid with a special odor. It is soluble in water at room temperature. The compound has good stability and low toxicity.
Use:
Adecainol is commonly used as a local anesthetic, which can be used for local anesthesia of skin and mucosal surfaces, and has analgesic and antipruritic effects. It is commonly used for skin injuries, wounds, burns, scalds and other conditions that require short-term pain relief and anesthesia.
Method:
The preparation method of Adecainol is mainly to react sulfuric acid and 4-sulfate anisole to obtain 4-sulfate anisole sulfate, this is then reacted with trimethyldisilane to give 4-sulfated anisole silyl ester, which is finally reacted with butyraldehyde to give 4-(trimethylsilyl) benzaldehyde. Finally, a polyoxyethylene (POE) reaction was used to produce the final product -4-(TRIETHYLSILYL)-3-BUTYN-1-OL.
Safety Information:
The use of Adecainol should follow the safety procedures. During use, care should be taken to avoid contact with skin and eyes to avoid irritation and damage. Users should wear appropriate personal protective equipment such as gloves and goggles. If inhaled or ingested, seek medical attention immediately. In addition, Adecainol should be stored in a light-shielded container, away from fire and high temperatures.
Nature:
Adecainol is a colorless to slightly yellow liquid with a special odor. It is soluble in water at room temperature. The compound has good stability and low toxicity.
Use:
Adecainol is commonly used as a local anesthetic, which can be used for local anesthesia of skin and mucosal surfaces, and has analgesic and antipruritic effects. It is commonly used for skin injuries, wounds, burns, scalds and other conditions that require short-term pain relief and anesthesia.
Method:
The preparation method of Adecainol is mainly to react sulfuric acid and 4-sulfate anisole to obtain 4-sulfate anisole sulfate, this is then reacted with trimethyldisilane to give 4-sulfated anisole silyl ester, which is finally reacted with butyraldehyde to give 4-(trimethylsilyl) benzaldehyde. Finally, a polyoxyethylene (POE) reaction was used to produce the final product -4-(TRIETHYLSILYL)-3-BUTYN-1-OL.
Safety Information:
The use of Adecainol should follow the safety procedures. During use, care should be taken to avoid contact with skin and eyes to avoid irritation and damage. Users should wear appropriate personal protective equipment such as gloves and goggles. If inhaled or ingested, seek medical attention immediately. In addition, Adecainol should be stored in a light-shielded container, away from fire and high temperatures.
Last Update：2024-04-09 21:00:56
Supplier List
Featured ProductsSpot supply
Product Name: 4-(Triethylsilyl)but-3-yn-1-ol Visit Supplier Webpage Request for quotationCAS: 160194-29-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 4-(Triethylsilyl)but-3-yn-1-ol Request for quotationCAS: 160194-29-6
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 4-(Triethylsilyl)but-3-yn-1-ol Visit Supplier Webpage Request for quotationCAS: 160194-29-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 4-(Triethylsilyl)but-3-yn-1-ol Visit Supplier Webpage Request for quotationCAS: 160194-29-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 4-(TRIETHYLSILYL)-3-BUTYN-1-OL Visit Supplier Webpage Request for quotationCAS: 160194-29-6
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Featured ProductsSpot supply
Product Name: 4-(Triethylsilyl)but-3-yn-1-ol Visit Supplier Webpage Request for quotationCAS: 160194-29-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 4-(Triethylsilyl)but-3-yn-1-ol Request for quotationCAS: 160194-29-6
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 4-(Triethylsilyl)but-3-yn-1-ol Visit Supplier Webpage Request for quotationCAS: 160194-29-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 4-(Triethylsilyl)but-3-yn-1-ol Visit Supplier Webpage Request for quotationCAS: 160194-29-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 4-(TRIETHYLSILYL)-3-BUTYN-1-OL Visit Supplier Webpage Request for quotationCAS: 160194-29-6
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
View History