194154-40-0
Cbz-Valine ganciclovir
CAS: 194154-40-0
Molecular Formula: C22H28N6O7
194154-40-0 - Names and Identifiers
194154-40-0 - Physico-chemical Properties
| Molecular Formula | C22H28N6O7 |
| Molar Mass | 488.49 |
| Density | 1.46 |
| Appearance | White solid |
| pKa | 9.32±0.20(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,2-8°C |
194154-40-0 - Introduction
Nature:
-Chemical formula: C_22H_29N_5O_8
-Molecular weight: 481.49g/mol
-Appearance: white or off-white crystalline powder
-Melting Point: 147-149 ℃
-Solubility: Soluble in polar organic solvents, such as alcohols and ketones, insoluble in water.
Use:
- Cbz-Valine ganciclovir is a derivative of the antiviral drug valganciclovir (Acyclovir), which can be used in the synthesis of valganciclovir.
- Cbz-Valine ganciclovir can also be used as a synthetic intermediate for other drugs, such as anti-cancer drugs.
Method:
The preparation of Cbz-Valine ganciclovir usually includes the following steps:
1. Valganciclovir and xylene are reacted under the action of alcohol and alkali to generate Cbz-Valine ganciclovir.
2. The product is purified by crystallization and washing processes using distillation of the solvent.
3. Further crystallization and purification can obtain Cbz-Valine ganciclovir with high purity.
Safety Information:
- Cbz-Valine ganciclovir is generally stable and non-flammable under normal conditions of use. However, care should still be taken to avoid contact with flammable substances.
-Appropriate chemical laboratory safety measures should be taken during handling and storage, including the wearing of protective glasses and gloves.
-If necessary, follow relevant safe operating procedures, such as using chemical purification columns to purify the product to ensure the safety of the work area.
-The substance needs to be properly stored and kept away from open flames and high temperature areas.
-In any case, the relevant regulations should be followed and the chemical safety data sheet (SDS) should be followed.
Please note that this is general information and should be used and operated in accordance with applicable regulations and guidelines.
Last Update：2024-04-09 15:17:54
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