203245-16-3
2,3,4-Trifluoroanisole
CAS: 203245-16-3
Molecular Formula: C7H5F3O
203245-16-3 - Names and Identifiers
| Name | 2,3,4-Trifluoroanisole |
| Synonyms | 2,3,4-Trifluoroanisole Benzene, 1,2,3-trifluoro-4-methoxy- Benzene, 1,2,3-trifluoro-4-methoxy- (9CI) |
| CAS | 203245-16-3 |
203245-16-3 - Physico-chemical Properties
| Molecular Formula | C7H5F3O |
| Molar Mass | 162.11 |
| Density | 1.285 |
| Boling Point | 156℃ |
| Flash Point | 54℃ |
| Storage Condition | Sealed in dry,Room Temperature |
203245-16-3 - Risk and Safety
| Hazard Symbols | F - Flammable |
| UN IDs | UN3271 |
| Hazard Class | 3 |
| Packing Group | III |
203245-16-3 - Introduction
2,3,4-Trifluoroanisole is an organic compound with the chemical formula C7H4F3O. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Boiling point: 70-72 ° C
-density: 1.45 g/cm ^ 3
-Solubility: Soluble in organic solvents, such as ethanol, acetone and dimethylformamide.
Use:
- 2,3,4-Trifluoroanisole can be used as a reagent in organic synthesis and is widely used in the fields of medicine, pesticide and material science.
-It can be used as an intermediate in drug synthesis, for example, for the synthesis of biologically active compounds.
-The compound can act as a solvent and catalyst in some chemical reactions.
-It can also be used in fluorination reactions in organic synthesis to introduce fluorine atoms.
Method:
The preparation method of 2,3,4-Trifluoroanisole usually involves the reaction of anisole with hydrogen trifluoride:
1. First, anisole is reacted with hydrogen trifluoride under reaction conditions to obtain the trifluoride of anisole (C6H5O · 3HF).
2. Then the trifluoride of anisole is defluoridated to remove hydrogen trifluoride under alkaline conditions to obtain 2,3,4-Trifluoroanisole.
Safety Information:
- 2,3,4-Trifluoroanisole is a chemical, and safety measures should be taken when using it.
-It may be irritating and toxic and should be avoided by inhalation, contact with skin and eyes.
-When using or handling, appropriate protective measures should be taken, such as wearing protective gloves, goggles and protective clothing.
-Store away from oxidants and fire sources.
Nature:
-Appearance: colorless liquid
-Boiling point: 70-72 ° C
-density: 1.45 g/cm ^ 3
-Solubility: Soluble in organic solvents, such as ethanol, acetone and dimethylformamide.
Use:
- 2,3,4-Trifluoroanisole can be used as a reagent in organic synthesis and is widely used in the fields of medicine, pesticide and material science.
-It can be used as an intermediate in drug synthesis, for example, for the synthesis of biologically active compounds.
-The compound can act as a solvent and catalyst in some chemical reactions.
-It can also be used in fluorination reactions in organic synthesis to introduce fluorine atoms.
Method:
The preparation method of 2,3,4-Trifluoroanisole usually involves the reaction of anisole with hydrogen trifluoride:
1. First, anisole is reacted with hydrogen trifluoride under reaction conditions to obtain the trifluoride of anisole (C6H5O · 3HF).
2. Then the trifluoride of anisole is defluoridated to remove hydrogen trifluoride under alkaline conditions to obtain 2,3,4-Trifluoroanisole.
Safety Information:
- 2,3,4-Trifluoroanisole is a chemical, and safety measures should be taken when using it.
-It may be irritating and toxic and should be avoided by inhalation, contact with skin and eyes.
-When using or handling, appropriate protective measures should be taken, such as wearing protective gloves, goggles and protective clothing.
-Store away from oxidants and fire sources.
Last Update：2024-04-09 19:05:47
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View History
203245-16-3
5764-82-9
Benzyl isocyanate
31396-35-7
103-72-0
7779-70-6
1-Butyl butyrate
6032-29-7
18698-99-2
Sodium stannate
5764-82-9
Benzyl isocyanate
31396-35-7
103-72-0
7779-70-6
1-Butyl butyrate
6032-29-7
18698-99-2
Sodium stannate