211308-81-5
2-Amino-5-chloro-3-iodopyridine
CAS: 211308-81-5
Molecular Formula: C5H4ClIN2
211308-81-5 - Names and Identifiers
211308-81-5 - Physico-chemical Properties
| Molecular Formula | C5H4ClIN2 |
| Molar Mass | 254.46 |
| Density | 2.139±0.06 g/cm3(Predicted) |
| Melting Point | 137-138°C |
| Boling Point | 306.9±42.0 °C(Predicted) |
| Flash Point | 139.41°C |
| Vapor Presure | 0.001mmHg at 25°C |
| Appearance | Yellow |
| pKa | 2.27±0.49(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Sensitive | Light Sensitive |
| Refractive Index | 1.708 |
| MDL | MFCD07644578 |
211308-81-5 - Risk and Safety
| Risk Codes | 22 - Harmful if swallowed |
| Hazard Class | IRRITANT |
| Packing Group | III |
211308-81-5 - Reference Information
| Uses | 2-amino-5-chloro-3-iodopyridine and its derivatives are a very useful class of aminopyridine derivatives. As an important pharmaceutical intermediate, it can be used to synthesize drugs for the treatment of digestive system diseases-pirenzepine. Pirenzepine is an excellent anti-ulcer drug, mainly used for the treatment of gastric and duodenal ulcers. Aminopyridine is used to synthesize anti-peptic ulcer drug pirenzepine, can also be used to synthesize diazepine anti-AIDS drugs, and can be used as a drug intermediate for pesticides. 2-Amino-5-chloro-3-iodopyridine is a useful synthetic intermediate. Rational design for highly selective tyrosine kinase inhibitors. It is also used to synthesize azaindole derivatives with antibacterial and antifungal activities. Therefore, the research on the synthesis of 2-amino -5-chloro -3-iodopyridine is of great significance and has a very broad prospect. |
Last Update：2024-04-09 20:52:54
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View History
211308-81-5
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1985607-66-6
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154934-99-3
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