279262-28-1
[4-(2-butoxyethoxy)phenyl]-Boronic acid
CAS: 279262-28-1
Molecular Formula: C12H19BO4
279262-28-1 - Names and Identifiers
279262-28-1 - Physico-chemical Properties
| Molecular Formula | C12H19BO4 |
| Molar Mass | 238.09 |
| Density | 1.09±0.1 g/cm3(Predicted) |
| Boling Point | 395.6±52.0 °C(Predicted) |
| pKa | 8.68±0.16(Predicted) |
279262-28-1 - Introduction
[4-(2-butoxyethoxy)phenyl]-Boronic acid, scientific name [4-(2-butoxyethoxy)phenyl]-Boronic acid, is an organic boron compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White to light yellow crystalline solid.
-Solubility: Soluble in many organic solvents, such as methanol, ethanol and dichloromethane, slightly soluble in water.
Use:
- [4-(2-butoxyethoxy)phenyl]-Boronic acid is an Organoboron reagent, commonly used as a ligand or reaction intermediate in metal-catalyzed reactions.
-It can be used for boronation reactions in organic synthesis, such as Suzuki coupling reaction and stile coupling reaction.
Method:
The preparation method of- [4-(2-butoxyethoxy)phenyl]-Boronic acid is more complicated. A commonly used method is to synthesize it through a multi-step reaction. The classical synthesis methods include the protection of Phenylboronic acid, the reaction of ethylene glycol with bromobutane, and the reaction of ethylene glycol with iodoethane.
Safety Information:
- [4-(2-butoxyethoxy)phenyl]-Boronic acid is relatively stable under normal conditions, but it is prone to decomposition under high temperature, high pressure or organic solvents.
-Be careful to avoid contact with skin and eyes, and avoid inhaling dust or gas.
-This compound should be stored in a low temperature, dry, well-ventilated place, away from fire and oxidizing agents.
Nature:
-Appearance: White to light yellow crystalline solid.
-Solubility: Soluble in many organic solvents, such as methanol, ethanol and dichloromethane, slightly soluble in water.
Use:
- [4-(2-butoxyethoxy)phenyl]-Boronic acid is an Organoboron reagent, commonly used as a ligand or reaction intermediate in metal-catalyzed reactions.
-It can be used for boronation reactions in organic synthesis, such as Suzuki coupling reaction and stile coupling reaction.
Method:
The preparation method of- [4-(2-butoxyethoxy)phenyl]-Boronic acid is more complicated. A commonly used method is to synthesize it through a multi-step reaction. The classical synthesis methods include the protection of Phenylboronic acid, the reaction of ethylene glycol with bromobutane, and the reaction of ethylene glycol with iodoethane.
Safety Information:
- [4-(2-butoxyethoxy)phenyl]-Boronic acid is relatively stable under normal conditions, but it is prone to decomposition under high temperature, high pressure or organic solvents.
-Be careful to avoid contact with skin and eyes, and avoid inhaling dust or gas.
-This compound should be stored in a low temperature, dry, well-ventilated place, away from fire and oxidizing agents.
Last Update：2024-04-09 02:00:44
