29741-10-4
Luteolin-7-O-β-D-glucuronide
CAS: 29741-10-4
Molecular Formula: C21H18O12
29741-10-4 - Names and Identifiers
29741-10-4 - Physico-chemical Properties
| Molecular Formula | C21H18O12 |
| Molar Mass | 462.36 |
| Density | 1.810±0.06 g/cm3(Predicted) |
| Melting Point | 242-244℃ |
| Boling Point | 892.5±65.0 °C(Predicted) |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
| Appearance | Powder |
| Color | Pale Yellow to Light Yellow |
| pKa | 2.73±0.70(Predicted) |
| Storage Condition | -20°C |
| Stability | Hygroscopic |
| MDL | MFCD04039811 |
| Physical and Chemical Properties | Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Kudiezi. |
29741-10-4 - Risk and Safety
| WGK Germany | 3 |
29741-10-4 - Reference
| Reference Show more | 1. Cao Yan, Li Ting, Xu Xia, Li Jun, Zhao Yunfang, Tu Pengfei, Song Yuelin. Rapid identification of chemical constituents of Artemisia capillaris by reversed phase chromatography-Hydrophilic Interaction Chromatography-predictive multiple reaction monitoring [J]. Chinese Journal of Traditional Chinese Medicine, 2019, 44(13):2667-2674. 2. Wang, Chu-Yang, et al. "Isolation of wheat mutants with higher grain phenolics to enhance anti-oxidant potential." Food chemistry 303 (2020): 125363.https://doi.org/10.1016/j.foodchem.2019.125363 3. [IF = 3.645] Guoyan Liu et al. "Isolation, purification, and identification of (Apium graveolens L. var. dulce Mill./Pers.)."J Sep Sci. 2017 Jan;40(2):472-479 4. [IF=7.514] Chu-Yang Wang et al."Isolation of wheat mutants with higher grain phenolics to enhance anti-oxidant potential."Food Chem. 2020 Jan;303:125363 5. [IF=2.72] Ji-Yu Nie et al."Antioxidant activity evaluation of rosemary ethanol extract and their cellular antioxidant activity toward HeLa cells."J Food Biochem. 2019 Jul;43(7):e12851 6. [IF=6.576] Junkun Pan et al."Inhibition of Dipeptidyl Peptidase-4 by Flavonoids: Structure-Activity Relationship, Kinetics and Interaction Mechanism."Frontiers in Nutrition. 2022; 9: 892426 |
29741-10-4 - Reference Information
| biological activity | Luteolin 7-O-glucuronide can be used as an effective free radical scavenger to inhibit the activity of matrix metalloproteinase (MMP). Its IC50 values for MMP-1,MMP-3,MMP-8,MMP-9 and MMP-13 are 17.63,7.99,11.42,12.85 and 0.03 μM respectively. |
| target | MMP-1 17.63 μ m (IC 50 ) MMP-3 7.99 μ m (IC 50 ) MMP-8 11.42 μ m (IC 50 ) MMP-9 12.85 μ m (IC 50 ) MMP13 0.03 μ m (IC 50 ) |
| chemical properties | yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from bitter dish. |
| use | for content determination/identification/pharmacological experiments, etc. |
Last Update：2024-04-09 20:52:54
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