368866-07-3
4-(Boc-amino)-1-Fmoc-piperdine-4-carboxylic Acid
CAS: 368866-07-3
Molecular Formula: C26H30N2O6
368866-07-3 - Names and Identifiers
368866-07-3 - Physico-chemical Properties
| Molecular Formula | C26H30N2O6 |
| Molar Mass | 466.53 |
| Density | 1.2464 (rough estimate) |
| Boling Point | 569.36°C (rough estimate) |
| pKa | 3.85±0.20(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.5300 (estimate) |
368866-07-3 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| HS Code | 29225090 |
368866-07-3 - Introduction
4-(Boc-amino)-Acid(4-(Boc-amino)-Acid) is an organic compound containing a piperidine ring and a fluorene ring in its structure. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystalline solid.
-Molecular weight: about 473.48g/mol.
-Melting point: about 135-139°C.
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide, dimethylformamide and acetonitrile.
Use:
-Chemical synthesis: 4-(Boc-amino)-Acid is often used as an important intermediate in organic synthesis. For example, in drug synthesis, it can be used to synthesize peptides, drugs and bioactive molecules.
-protecting group: Boc and Fmoc groups are often used as protecting groups for amino groups to protect the reactivity of amino groups.
Preparation Method:
4-(Boc-amino)-The preparation method of Acid is more complicated and involves multi-step reactions. The following is a common preparation method:
1. synthesis of Boc-protected piperidine by chemical reaction.
2. The Boc-protected piperidine is reacted with Fmoc-Cl to generate 4-(Boc-amino)-1-Fmoc-piperdine.
3. Finally, 4-(Boc-amino)-1-Fmoc-piperdine is reacted with an appropriate acid to remove the Boc protecting group to obtain 4-(Boc-amino)-piperidine Acid.
Safety Information:
4-(Boc-amino)-The Acid is generally safe under correct use and storage. However, it is a chemical, and it is still necessary to follow the safe handling of chemicals, such as wearing appropriate personal protective equipment, avoiding contact with skin and eyes, and maintaining a well-ventilated working environment. In addition, the compound may have a certain stimulating effect on the human body, so it should be used with caution.
Nature:
-Appearance: White crystalline solid.
-Molecular weight: about 473.48g/mol.
-Melting point: about 135-139°C.
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide, dimethylformamide and acetonitrile.
Use:
-Chemical synthesis: 4-(Boc-amino)-Acid is often used as an important intermediate in organic synthesis. For example, in drug synthesis, it can be used to synthesize peptides, drugs and bioactive molecules.
-protecting group: Boc and Fmoc groups are often used as protecting groups for amino groups to protect the reactivity of amino groups.
Preparation Method:
4-(Boc-amino)-The preparation method of Acid is more complicated and involves multi-step reactions. The following is a common preparation method:
1. synthesis of Boc-protected piperidine by chemical reaction.
2. The Boc-protected piperidine is reacted with Fmoc-Cl to generate 4-(Boc-amino)-1-Fmoc-piperdine.
3. Finally, 4-(Boc-amino)-1-Fmoc-piperdine is reacted with an appropriate acid to remove the Boc protecting group to obtain 4-(Boc-amino)-piperidine Acid.
Safety Information:
4-(Boc-amino)-The Acid is generally safe under correct use and storage. However, it is a chemical, and it is still necessary to follow the safe handling of chemicals, such as wearing appropriate personal protective equipment, avoiding contact with skin and eyes, and maintaining a well-ventilated working environment. In addition, the compound may have a certain stimulating effect on the human body, so it should be used with caution.
Last Update：2024-04-09 21:00:56
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View History
368866-07-3
115956-13-3
106359-89-1
425378-68-3
56601-42-4
152126-31-3
n-壬基溴化锌
17896-21-8
187746-94-7
134615-24-0
115956-13-3
106359-89-1
425378-68-3
56601-42-4
152126-31-3
n-壬基溴化锌
17896-21-8
187746-94-7
134615-24-0