380626-81-3
ethyl 4-amino-6-chloronicotinate
CAS: 380626-81-3
Molecular Formula: C8H9ClN2O2
380626-81-3 - Names and Identifiers
380626-81-3 - Physico-chemical Properties
| Molecular Formula | C8H9ClN2O2 |
| Molar Mass | 200.62 |
| Density | 1.326±0.06 g/cm3(Predicted) |
| Boling Point | 335.8±37.0 °C(Predicted) |
| pKa | 2.75±0.42(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
380626-81-3 - Introduction
ethyl 4-amino-6-chloronicotinate is an organic compound with the chemical formula C8H8ClNO2. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: ethyl 4-amino-6-choronicotinate is a colorless or slightly yellow crystalline solid.
-Solubility: Its solubility in water is lower, and it is easier to dissolve in organic solvents such as ethanol and dimethylformamide (DMF).
-Melting point: Its melting point range is approximately 135-137 ° C.
Use:
-Drug synthesis: ethyl 4-amino-6-choronicotinate is widely used as an intermediate in the field of drug synthesis, and is used to synthesize some biologically active compounds, such as antibiotics, anti-cancer drugs and anti-inflammatory drugs.
Method:
- ethyl 4-amino-6-chloronicotinate can be formed by reacting chloronicotinate with ethanol and ammonia. Specific synthetic methods can be found in the Handbook of organic synthesis.
Safety Information:
- ethyl 4-amino-6-choronicotinate needs to pay attention to safety measures during use and storage to prevent inhalation, intake or skin contact.
-It may be irritating to the eyes, skin and respiratory tract, so it is necessary to wear appropriate protective equipment such as chemical goggles, gloves and protective masks when handling.
-During use and storage, keep it away from fire sources and flammable substances, and keep the storage container sealed and placed in a cool, dry place.
Please note: When using any chemical substance, you must follow the correct laboratory procedures and take appropriate safety measures based on the detailed information provided in the chemical safety data sheet (MSDS).
Nature:
-Appearance: ethyl 4-amino-6-choronicotinate is a colorless or slightly yellow crystalline solid.
-Solubility: Its solubility in water is lower, and it is easier to dissolve in organic solvents such as ethanol and dimethylformamide (DMF).
-Melting point: Its melting point range is approximately 135-137 ° C.
Use:
-Drug synthesis: ethyl 4-amino-6-choronicotinate is widely used as an intermediate in the field of drug synthesis, and is used to synthesize some biologically active compounds, such as antibiotics, anti-cancer drugs and anti-inflammatory drugs.
Method:
- ethyl 4-amino-6-chloronicotinate can be formed by reacting chloronicotinate with ethanol and ammonia. Specific synthetic methods can be found in the Handbook of organic synthesis.
Safety Information:
- ethyl 4-amino-6-choronicotinate needs to pay attention to safety measures during use and storage to prevent inhalation, intake or skin contact.
-It may be irritating to the eyes, skin and respiratory tract, so it is necessary to wear appropriate protective equipment such as chemical goggles, gloves and protective masks when handling.
-During use and storage, keep it away from fire sources and flammable substances, and keep the storage container sealed and placed in a cool, dry place.
Please note: When using any chemical substance, you must follow the correct laboratory procedures and take appropriate safety measures based on the detailed information provided in the chemical safety data sheet (MSDS).
Last Update：2024-04-09 20:49:11
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View History
380626-81-3
1260007-55-3
119637-67-1
Faropenem sodium hemipentahydrate
4-溴-2-碘吡啶
114224-28-1
2,2'-dithiodianiline
二甲基氧化锡
氨甲基膦酸
CARBONIC ACID ETHYL METHYL ESTER
1260007-55-3
119637-67-1
Faropenem sodium hemipentahydrate
4-溴-2-碘吡啶
114224-28-1
2,2'-dithiodianiline
二甲基氧化锡
氨甲基膦酸
CARBONIC ACID ETHYL METHYL ESTER