52805-46-6
3-HYDROXY-4-METHOXYBENZONITRILE
CAS: 52805-46-6
Molecular Formula: C8H7NO2
52805-46-6 - Names and Identifiers
| Name | 3-HYDROXY-4-METHOXYBENZONITRILE |
| Synonyms | ISOVANILLONITRILE 2-Methoxy-5-cyanophenol 5-Cyano-2-methoxyphenol 3-Hydroxy-4-methoxybenzonitril 3-HYDROXY-4-METHOXYBENZONITRILE Benzonitrile, 3-hydroxy-4-Methoxy- 3-HYDROXY-4-METHOXYBENZONITRILE (ISOVANILLONITRILE) Gefitinib IMpurity (3-Hydroxy-4-Methoxybenzonitrile) |
| CAS | 52805-46-6 |
| InChI | InChI=1/C8H7NO2/c1-11-8-3-2-6(5-9)4-7(8)10/h2-4,10H,1H3 |
52805-46-6 - Physico-chemical Properties
| Molecular Formula | C8H7NO2 |
| Molar Mass | 149.15 |
| Density | 1.24±0.1 g/cm3(Predicted) |
| Melting Point | 124 °C |
| Boling Point | 300.8±27.0 °C(Predicted) |
| Flash Point | 135.7°C |
| Vapor Presure | 0.000613mmHg at 25°C |
| Appearance | Bright light brown crystalline powder |
| pKa | 8.59±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.568 |
| MDL | MFCD02258854 |
52805-46-6 - Risk and Safety
| HS Code | 29269090 |
52805-46-6 - Introduction
It is an organic compound with the formula C8H7NO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystal or crystalline powder.
-Melting point: about 110-112 degrees Celsius.
-Solubility: Soluble in many organic solvents, such as alcohols, esters and ethers, insoluble in water.
Use:
-is an important organic synthesis intermediate, which is often used as a starting material in drug synthesis. It can be used as a synthetic raw material for anti-inflammatory drugs and cholinesterase inhibitors.
Preparation Method:
-or can be prepared by the oxidation of hydroxybenzonitrile by parafrin. First, p-meflurane is reacted with an oxidizing agent, such as hydrogen peroxide, to form p-methoxybenzonitrile. The p-methoxybenzonitrile is then subjected to boric acid catalyzed hydrogenation to reduce the methoxy group to a hydroxyl group.
Safety Information:
-Toxicity information is limited. However, like other chemicals, it should follow appropriate safe handling procedures in a laboratory environment, such as wearing personal protective equipment (gloves, glasses, laboratory coats, etc.), and storing in a dry, well-ventilated place. For detailed safety information, reference should be made to the relevant safety data sheet for the compound.
Nature:
-Appearance: White crystal or crystalline powder.
-Melting point: about 110-112 degrees Celsius.
-Solubility: Soluble in many organic solvents, such as alcohols, esters and ethers, insoluble in water.
Use:
-is an important organic synthesis intermediate, which is often used as a starting material in drug synthesis. It can be used as a synthetic raw material for anti-inflammatory drugs and cholinesterase inhibitors.
Preparation Method:
-or can be prepared by the oxidation of hydroxybenzonitrile by parafrin. First, p-meflurane is reacted with an oxidizing agent, such as hydrogen peroxide, to form p-methoxybenzonitrile. The p-methoxybenzonitrile is then subjected to boric acid catalyzed hydrogenation to reduce the methoxy group to a hydroxyl group.
Safety Information:
-Toxicity information is limited. However, like other chemicals, it should follow appropriate safe handling procedures in a laboratory environment, such as wearing personal protective equipment (gloves, glasses, laboratory coats, etc.), and storing in a dry, well-ventilated place. For detailed safety information, reference should be made to the relevant safety data sheet for the compound.
Last Update：2024-04-09 21:01:54
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View History
52805-46-6
25103-58-6
196304-02-6
酰嘧磺隆
O-Phenyl carbonochloridothioate
144582-55-8
85-85-8
Nialk
CeriumoxideREO
克百威颗粒剂
25103-58-6
196304-02-6
酰嘧磺隆
O-Phenyl carbonochloridothioate
144582-55-8
85-85-8
Nialk
CeriumoxideREO
克百威颗粒剂