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55077-30-0

Aclatonium napadisilate

CAS: 55077-30-0

Molecular Formula: C30H44N2O14S2

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55077-30-0 - Names and Identifiers

Name Aclatonium napadisilate
Synonyms Abovis
Aclatonium
Aclatonium napadisilate
aclatonium napadisylate
aclatonium napadisilate
1,5-Naphthalenedisulfonic acid, ion(2-), bis[2-[2-(acetyloxy)-1-oxopropoxy]-N,N,N-trimethylethanaminium] (9CI)
2-(2-acetyloxypropanoyloxy)ethyl-[2-[2-(2-acetyloxypropanoyloxy)ethyl-dimethyl-ammonio]ethyl]-dimethyl-azanium naphthalene-1,5-disulfonate
CAS 55077-30-0
EINECS 1592732-453-0

55077-30-0 - Physico-chemical Properties

Molecular FormulaC30H44N2O14S2
Molar Mass720.80536
Melting Point189-191°
AppearanceColor Crystals
Physical and Chemical PropertiesChemical properties crystal. Melting point 189-191 ℃.
UseUse cholinergic drugs.

55077-30-0 - Risk and Safety

ToxicityLD50 in mice: 15 g/kg orally, 826 mg/kg s.c. (Miura); in dogs: >10 g/kg orally (Takai)

55077-30-0 - Upstream Downstream Industry

Raw MaterialsIsopropyl acetate
Choline hydroxide

55077-30-0 - Uses and synthesis methods

Pharmacodynamics

Ethylcholine naphthalene disulfonate is a choline-like drug that directly acts on smooth muscle choline receptors. It can excite gastrointestinal smooth muscle to produce contraction, promote gastrointestinal emptying, and promote bile discharge from the gallbladder and common bile duct. However, it has no effect on the secretion of gastric juice, the acidity of gastric juice and the concentration of pepsin.

clinical application

chronic gastritis, biliary dyskinesia, digestive dysfunction after digestive tract surgery such as nausea, vomiting, loss of appetite and abdominal distension.

Production method

Suspend bis (choline)-naphthalene-1, 5 disulfonate in acetonitrile, add lactic anhydride diacetate, and heat the mixture to reflux for 3 hours. The resulting product is cooled to precipitate crystallization. Filtered products.

category

Toxic substances

Toxicity classification

low toxicity

Acute toxicity

oral-rat LDL0: 15000 mg/kg; Oral-mouse LD50:15000 mg/kg

flammability hazard characteristics

Combustible; heat decomposition releases toxic nitrogen oxides and sulfur oxide smoke

storage and transportation features

Warehouse ventilation low temperature drying

Fire extinguishing agent

Dry powder, foam, sand, water

Last Update:2024-04-09 01:59:50
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Product Name: Aclatonium napadisylate Visit Supplier Webpage Request for quotation
CAS: 55077-30-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Aclatonium Napadisilate Visit Supplier Webpage Request for quotation
CAS: 55077-30-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
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View History
55077-30-0
123-70-6
94956-98-6
179617-08-4
环烷酸钙
175201-90-8
811-51-8
Raw Materials for 55077-30-0
Isopropyl acetate
Choline hydroxide
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