6132-04-3
sodium citrate, dihydrate
CAS: 6132-04-3
Molecular Formula: C6H5Na3O7·2H2O
6132-04-3 - Names and Identifiers
| Name | sodium citrate, dihydrate |
| Synonyms | ANTI-BABOON IGM, BIOTIN sodium citrate, dihydrate CITRIC ACID NA3-SALT 2H2O CITRIC ACID, 3NA, DIHYDRATE Trisodium citrate dihydrate Citric acid trisodium salt dihydrate methyl 2-amino-4-(4-tert-butylphenyl)thiophene-3-carboxylate 1,2,3-Propanetricarboxylicacid,2-hydroxy-,trisodiumsalt,dihydrate |
| CAS | 6132-04-3 |
| EINECS | 200-675-3 |
| InChI | InChI=1/C16H19NO2S/c1-16(2,3)11-7-5-10(6-8-11)12-9-20-14(17)13(12)15(18)19-4/h5-9H,17H2,1-4H3 |
6132-04-3 - Physico-chemical Properties
| Molecular Formula | C6H5Na3O7·2H2O |
| Molar Mass | 294.1 |
| Density | 1.152g/cm3 |
| Melting Point | 300℃ |
| Boling Point | 404.2°C at 760 mmHg |
| Flash Point | 198.2°C |
| Water Solubility | 720 g/L (25℃) |
| Solubility | Soluble in water (29.4 g/l) at 20 °C. Insoluble in ethanol |
| Vapor Presure | 9.63E-07mmHg at 25°C |
| Appearance | White crystalline particles or powder |
| Storage Condition | Room Temprature |
| Sensitive | Easily absorbing moisture |
| Refractive Index | 1.58 |
| MDL | MFCD00150031 |
| Physical and Chemical Properties | density 1.76 |
| Use | Used as food additives, electroplating industry with complexing agent, buffer, pharmaceutical industry used in the manufacture of anti-blood clotting drugs, light industry used as detergent additives |
6132-04-3 - Risk and Safety
| Safety Description | S24/25 - Avoid contact with skin and eyes. |
6132-04-3 - Upstream Downstream Industry
| Raw Materials | Sodium carbonate Sulfuric acid Citric acid Sodium hydroxide Calcium carbonate Sodium carbonate |
6132-04-3 - Reference
| Reference Show more | 1. Li Huan Tong Xu Zewen Guo Xiaomin Peng Lisa Cao Yong Xiao Su Yao. Optimization of low-temperature continuous phase change extraction of anthocyanins from blueberry and its components analysis [J]. Food Science and Technology 2020 45(05):233-240. 2. Ning Yu, Chen Yu, Yan Zhiming. Sulfonamides in milk based on SNW-1 magnetic solid phase extraction [J]. Fujian Journal of Agricultural Sciences, 2020,35(10):1154-1161. 3. Jiang, Xiao, et al. "Colorimetric and fluorometric dual-channel proportional determination of fundamental cymoxanol based on analyte-induced." Microchimica Acta 186.8 (2019): 1-12.https:// 4. Jiang, Xiao, et al. "Colorimetric and fluorometric dual-channel ratiometric determination of fungicide cymoxanil based on analyte-induced aggregation of silver nanoparticles and dually emitting carbon dots." Microchimica Acta 186.8 (2019): 1-12.https:// 5. [IF=13.273] Qinyuan Hong et al."Shell-thickness-induced spontaneous inward migration of mercury in porous ZnO@CuS for gaseous mercury immobilization."Chem Eng J. 2021 Sep;420:127592 6. [IF=7.514] Fei Zhou et al."Influence of processing methods and exogenous selenium species on the content and in vitro bioaccessibility of selenium in Pleurotus eryngii."Food Chem. 2021 Feb;338:127661 7. [IF=6.953] Xi Yang et al."Structuring oil-in-water emulsion by forming egg yolk/alginate complexes: Their potential application in fabricating low-fat mayonnaise-like emulsion gels and redispersible solid emulsions."Int J Biol Macromol. 2020 Mar;147:595 8. [IF=4.616] Zeren Liang et al."Comparative study of serum sample preparation methods in aggregation-based plasmonic sensing."Analyst. 2021 Jan;145(24):7946-7955 9. [IF=5.548] Zijing Wu et al."Gold core @ platinum shell nanozyme-mediated magnetic relaxation switching DNA sensor for the detection of Listeria monocytogenes in chicken samples."Food Control. 2022 Jul;137:108916 10. [IF=6.558] Changhao Bao et al."Simultaneous determination of aesculin and aesculetin and their interactions with DNA using carbon fiber microelectrode modified by Pt-Au bimetallic nanoparticles."Anal Chim Acta. 2022 Apr;1202:339664 11. [IF=8.928] Huaxin Li et al."High Performance 3D Self-Supporting Cu−Bi Aerogels for Electrocatalytic Reduction of CO2 to Formate."ChemSusChem. 2022 Feb 24 |
6132-04-3 - Nature
Open Data Verified Data
white crystals, granules or powders. Tasteless, stable in the air. 150 deg C loss of crystal water, continue to heat the decomposition. Dissolved in 1.3 parts of water, 0.6 parts of boiling water, the solution is slightly alkaline, pH value is about 8. Insoluble in ethanol.
Last Update：2025-06-10 22:55:16
6132-04-3 - Preparation Method
Open Data Verified Data
obtained by neutralization of citric acid with sodium hydroxide or sodium bicarbonate.
Last Update：2022-01-01 09:25:34
6132-04-3 - Standard
Authoritative Data Verified Data
This product is 2-hydroxypropane-1, 2, 3-tricarboxylic acid sodium dihydrate. Citric acid dissolved in water, slowly add the calculated amount of sodium carbonate until the bubble disappeared, filtered, evaporated to dryness. The content of CfiH5Na30 7 shall not be less than 99.0% calculated as dry product.
Last Update：2024-01-02 23:10:35
6132-04-3 - Trait
Authoritative Data Verified Data
- This product is colorless crystal or white crystalline powder; Odorless; Slightly deliquescent in wet air and weathered in hot air.
- This product is soluble in water and insoluble in ethanol.
Last Update：2022-01-01 11:23:55
6132-04-3 - Introduction
No smell, salty and cool taste, stable in the air, water loss at 150 ℃. Soluble in water (1.3 parts cold water, 0.6 parts boiling water), insoluble in ethanol. The aqueous solution is slightly alkaline to litmus, with a pH of about 8 and a 1.857 relative density. Correct the acidity of urine. Sodium citrate dihydrate is used as a buffer, pH control agent, emulsifier, chelating agent, etc. in the food industry.
Last Update：2022-10-16 17:27:06
6132-04-3 - Application
Open Data Verified Data
for the preparation of bacterial culture media, blood anticoagulants, correction of urinary acidity and the pharmaceutical industry.
Last Update：2025-08-19 16:24:40
6132-04-3 - Differential diagnosis
Authoritative Data Verified Data
The Goods Show the identification of sodium salt and citrate reaction (General 0301).
Last Update：2022-01-01 11:23:55
6132-04-3 - Safety
Open Data Verified Data
rats were injected intraperitoneally with LD50: 6.0 mmol/kg.
Last Update：2022-01-01 09:25:34
6132-04-3 - Exam
Authoritative Data Verified Data
alkalinity
take this product l.O g, add water 20ml dissolved, add phenolphthalein indicator solution 1 drop and sulfuric acid titration solution (0. 05mol/L)0. 1 0ml, not shown in red.
clarity and color of solution
take 2.5g of this product, Add 10ml of water to dissolve, check according to law (General Rule 901 and general rule 0902), the solution should be clear and colorless.
chloride
take 0.60g of this product and check it according to law (General rule 0801). Compared with the control solution made of 6.0 ml of standard sodium chloride solution, it should not be more concentrated (0 .01%).
sulfate
take this product 0,50g, check according to law (General rule 0802), compared with the standard potassium sulfate solution 2. 5ml made of the control solution, not more concentrated (0. 05%).
tartrate
Take lg of this product, put it in a test tube, add 2M l of water to dissolve, add each lm l of potassium acetate test solution and acetic acid, rub the tube wall with a glass rod, and do not precipitate crystalline precipitate.
easily carbonized
take 0.40g of this product, add sulfuric acid [containing 3 0 4 94.5% ~ 95.5%(g/g>] 5 m l, heat for 1 hour, immediately cool, inspection according to law (General rule 0842), compared with the yellow or yellow-green No. 8 Standard Colorimetric solution, shall not be deeper.
loss on drying
take this product, dry to constant weight at 180 * C, weight loss should be 1 0.0 ~ 13.0% (General rule 0831).
calcium or oxalate
take this product 2. After adding 20ml of fresh boiling cold water to dissolve, add 0 .4m l and 2ml of ammonium oxalate solution, shake well and place for 1 hour. In case of turbidity, take 0.125g of calcium carbonate with standard calcium solution and put it in a 500ml measuring flask, add water 5M l and hydrochloric acid 0. 5M l of the mixture solution to dissolve, and diluted with water to the scale, shake, each lm l containing calcium (Ca)O.lOmg]1. Compared with the control solution made of 0M l, it should not be more concentrated (0.005%). In the above inspection, if there is no turbidity, should take the product l.O g, add water lm l and dilute hydrochloric acid 3M l mixture to dissolve, add 90% ethanol 4M l and calcium chloride test solution 4 drops, stand for 1 hour, no turbidity.
Heavy metals
take 2.0g of this product, Add 10ml of water to dissolve, Add 10ml of dilute acetic acid and an appropriate amount of water to make 25ml, and check according to law (General rule 0821 first law), containing no more than 5 parts per million of heavy metals.
arsenic salt
Take 2. 0g of this product, add 23ml of water to dissolve, add 5ml of hydrochloric acid, check according to law (General rule 0822 first law), should comply with the provisions (0.0001%).
bacterial endotoxin
take this product, check according to law (General 1143), the amount of endotoxin per 1 mg of sodium citrate should be less than 0. 25EU (for injection).
Last Update：2022-01-01 11:23:56
6132-04-3 - Content determination
Authoritative Data Verified Data
take this product about 80mg, precision weighing, add glacial acetic acid 30ml dissolved, add acetic anhydride 10ml, according to the potentiometric titration method (General rule 0701>, with perchloric acid titration solution (0. lm o l/L) titration, and the results of the titration were corrected with a blank test. Each lm l of high gas acid titration solution (0.1 M o l/L) corresponds to 8.602 mg of C8H5Na30 7.
Last Update：2022-01-01 11:23:56
6132-04-3 - Category
Authoritative Data Verified Data
pharmaceutical excipients, buffers, chelating agents and antioxidant synergists.
Last Update：2022-01-01 11:23:57
6132-04-3 - Storage
Authoritative Data Verified Data
sealed storage.
Last Update：2022-01-01 11:23:57
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Tel: +86 19849939632
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Product Name: Sodiumcitratetribasicdihydrate Request for quotationCAS: 6132-04-3
Tel: 400-968-2212
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Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Multiple SpecificationsSpot supply
Product Name: Sodium citrate dihydrate, United States Pharmacopeia (USP) Reference Standard Visit Supplier Webpage Request for quotationCAS: 6132-04-3
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
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Product Name: Sodium citrate dihydrate Visit Supplier Webpage Request for quotationCAS: 6132-04-3
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View History
6132-04-3
100047-52-7
呋喃丹
2-methyl-4-nitro-benzonitrile
1073-21-8
1184136-10-4
1260780-39-9
94838-82-1
3411-03-8
1016-58-6
100047-52-7
呋喃丹
2-methyl-4-nitro-benzonitrile
1073-21-8
1184136-10-4
1260780-39-9
94838-82-1
3411-03-8
1016-58-6
Raw Materials for 6132-04-3