| Molecular Formula | C18H18F2N2O4 |
| Molar Mass | 364.34 |
| Density | 1.363±0.06 g/cm3(Predicted) |
| Boling Point | 657.6±55.0 °C(Predicted) |
| pKa | 8.68±0.25(Predicted) |
| Storage Condition | -20℃ |
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.745 ml | 13.723 ml | 27.447 ml |
| 5 mM | 0.549 ml | 2.745 ml | 5.489 ml |
| 10 mM | 0.274 ml | 1.372 ml | 2.745 ml |
| 5 mM | 0.055 ml | 0.274 ml | 0.549 ml |
| biological activity | emd63883 is a highly selective inhibitor of serum- and glucocorticoid-inducible kinase 1 (SGK1), the IC50 value was 3 μm. Emd6386 83 has antihypertensive efficacy and antitumor activity. |
| Target | TargetValue SGK1 (Cell-free assay) 3 μm |
| Target | Value |
| SGK1 (Cell-free assay) | 3 μM |