L-838417
L-838417
CAS: 286456-42-6
Molecular Formula: C19H19F2N7O
L-838417 - Names and Identifiers
L-838417 - Physico-chemical Properties
| Molecular Formula | C19H19F2N7O |
| Molar Mass | 399.4 |
| Melting Point | 196-198°C |
| Solubility | DMSO: ≥20mg/mL |
| Appearance | powder |
| Color | white to off-white |
| Storage Condition | Store at +4°C |
| In vivo study | L-838417 (1.0 mg/kg) produces anxiolytic effects in adult rat, as indexed by a transformation of social avoidance into preference and an increase in social investigation. L-838417 (2.0 mg/kg) eliminates social avoidance, but has no anxiolytic effects on social investigation. L-838417 (0.5 mg/kg) reverses the anxiogenic effects of prior stress regardless of age, but with doses ≥ 1 mg/kg decreases social investigation, an effect possibly due in part to locomotor-impairing effects of this compound. Animal Model: Male and female adolescent and adult Sprague–Dawley rats. Dosage: 0, 0.5, 1.0, 2.0, or 4.0 mg/kg. Administration: IP. Result: Adolescents required a higher dose (2 mg/kg) to attenuate their social avoidance. The lowest dose of 0.5 mg/kg was sufficient to reverse the anxiogenic effects of repeated restraint as reflected by a significant increase in the coefficient relative to vehicle-treated animals. |
L-838417 - Risk and Safety
| WGK Germany | 3 |
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Multiple SpecificationsSpot supply
Product Name: L-838417 (Standard) Visit Supplier Webpage Request for quotationCAS: 286456-42-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
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Product Name: L-838417 Visit Supplier Webpage Request for quotation
CAS: 286456-42-6
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CAS: 286456-42-6
Tel: 18301782025
Email: 3008007409@qq.com
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