Losartan
Losartan
CAS: 114798-26-4
Molecular Formula: C22H23ClN6O
Losartan - Names and Identifiers
| Name | Losartan |
| Synonyms | LOS dup89 Losartan LOSARTAN nyl)-4-yl)methyl)- LosartanC22H23C1N60 2-butyl-4-chloro-1-[p-(o-1h-tetrazol-5-ylphenyl)benzyl]imidazole-5- methanol [2-butyl-5-chloro-3-[[4-phenyl-3-(1H-tetrazol-5-yl)phenyl]methyl]imidazol-4-yl]methanol (2-butyl-4-chloro-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol 1h-imidazole-5-methanol, 2-butyl-4-chloro-1-((2'-(1h-tetrazol-5-yl)(1,1'- biphenyl)-4-yl)methyl)- (1-((2-(1H-TETRAZOL-5-YL)BIPHENYL-4-YL)METHYL)-2-BUTYL-4-CHLORO-1H-IMIDAZOL-5-YL)METHANOL (LOSARTAN) |
| CAS | 114798-26-4 |
| EINECS | 601-329-8 |
| InChI | InChI=1/C22H23ClN6O/c1-2-3-9-20-24-21(23)19(14-30)29(20)13-15-10-11-17(16-7-5-4-6-8-16)18(12-15)22-25-27-28-26-22/h4-8,10-12,30H,2-3,9,13-14H2,1H3,(H,25,26,27,28) |
Losartan - Physico-chemical Properties
| Molecular Formula | C22H23ClN6O |
| Molar Mass | 422.91 |
| Density | 1.35±0.1 g/cm3(Predicted) |
| Melting Point | 183-184 C |
| Boling Point | 682.0±65.0 °C(Predicted) |
| Flash Point | 369°C |
| Water Solubility | 4.8mg/L at 20℃ |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 0.002Pa at 20℃ |
| Appearance | Pale yellow solid |
| Color | White to Off-White |
| pKa | 5-6(at 25℃) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.68 |
| Physical and Chemical Properties | Light yellow solid, melting point 183.5~184.5 °c. pKa:5~6. |
| Use | The first oral non-peptide angiotensin II receptor antagonist. Mainly used for primary hypertension. |
Losartan - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
Losartan - Reference
| Reference Show more | 1. Pang Xin, Zhang Jianwei, Pang Xinxin, Chen Xiaoyong, Xie Hongxia. Geniposide alleviates inflammatory response and oxidative stress in IgA nephropathy model mice by regulating NLRP3 [J]. Journal of Immunology, 2020,36(10):870-876. |
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Product Name: Losartan Visit Supplier Webpage Request for quotationCAS: 114798-26-4
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Mobile: +86-18621343501
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Product Name: Losartan Visit Supplier Webpage Request for quotationCAS: 114798-26-4
Tel: 609-228-6898
Email: sales@medchemexpress.com
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Mobile: 609-228-6898
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Product Name: Losartan Visit Supplier Webpage Request for quotationCAS: 114798-26-4
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
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