ONO-4059
ONO-4059 (analog)
CAS: 1351635-67-0
Molecular Formula: C25H24N6O3
ONO-4059 - Names and Identifiers
ONO-4059 - Physico-chemical Properties
| Molecular Formula | C25H24N6O3 |
| Molar Mass | 456.5 |
| Density | 1.364±0.06 g/cm3(Predicted) |
| Boling Point | 714.0±70.0 °C(Predicted) |
| Solubility | DMSO: ≥ 29 mg/mL |
| pKa | 3.15±0.20(Predicted) |
| Storage Condition | -20℃ |
| In vitro study | In TMD-8 cells, ONO-4059 inhibited cell growth with an IC50 of 3.59 nM and induced apoptosis. ONO-4059 in combination with doxorubicin, etoposide, Vincristine or dexamethasone, increased apoptotic rate. |
ONO-4059 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.191 ml | 10.953 ml | 21.906 ml |
| 5 mM | 0.438 ml | 2.191 ml | 4.381 ml |
| 10 mM | 0.219 ml | 1.095 ml | 2.191 ml |
| 5 mM | 0.044 ml | 0.219 ml | 0.438 ml |
Last Update：2024-01-02 23:10:35
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