epibrassinolide
epibrassinolide
CAS: 78821-43-9;72962-43-7
Molecular Formula: C28H48O6
epibrassinolide - Names and Identifiers
epibrassinolide - Physico-chemical Properties
| Molecular Formula | C28H48O6 |
| Molar Mass | 480.68 |
| Density | 1.141±0.06 g/cm3(Predicted) |
| Melting Point | 256°C |
| Boling Point | 633.7±55.0 °C(Predicted) |
| Specific Rotation(α) | D27 +16° |
| Flash Point | 202.3°C |
| Solubility | The solubility in water is 5mg/L, soluble in methanol, tetrahydrofuran, acetone and other organic solvents. |
| Vapor Presure | 1.01E-18mmHg at 25°C |
| Appearance | White crystalline powder |
| Color | White to Off-White |
| pKa | 14.27±0.70(Predicted) |
| Storage Condition | -20°C |
| Refractive Index | 1.535 |
| MDL | MFCD00133310 |
| Physical and Chemical Properties | White crystal powder |
| Use | Is a broad-spectrum efficient plant growth regulator, on a variety of economic crops have significant effect on increasing production, can effectively regulate the various aspects of plant growth |
| In vitro study | Epibrassinolide (EBR) is a biologically active compound of the brassinosteroids, steroid-derived plant growth regulator family. Cells are incubated with various doses (0-100 μM) of Epibrassinolide for 24 or 48 h and cell viability is determined by MTT assay. Epibrassinolide induced cell viability loss in dose- and time-dependent manner compared to untreated samples in LNCaP and DU145 prostate cancer cells. Increasing concentrations of Epibrassinolide is more effective on LNCaP cell viability loss than DU145 cells suggesting that androgen-dependent cells are more sensitive to Epibrassinolide than androgen-independent prostate cancer cells. In further experiments, 25 μM Epibrassinolide is selected due to its moderate cytotoxic effect on both cell lines. The effect of Epibrassinolide treatment is examined on cell proliferation by counting the cell number within 96 h. A higher and earlier inhibition of cell proliferation is observed in LNCaP than DU145 cells. |
epibrassinolide - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| WGK Germany | 3 |
| HS Code | 29372900 |
epibrassinolide - Reference
| Reference Show more | 1. Ye Qinglei Li Zhi Wang Lizhi Zhang Yuehui Zhang Jing Sun Xiaodong. Effects of different exogenous hormones on seed germination of Mulberry [J]. Heilongjiang Agricultural Sciences 2015(11):78-80. 2. Guo Shuhua, Zhang Shuhui, Liu Bailin, Liu Xiaohong, du Yuanpeng. Effects of different plant growth regulator combinations on quality of summer Black Grape [J]. Deciduous Fruit Tree 2016 48(04):6-9. 3. High State year. Effects of brassinolide on spring shoots and related indexes of Camellia oleifera [J]. Journal of Anhui Agricultural Sciences, v.42;No.434(01):132-134. 4. Wu, Jin-dong. Regulation effect of brassinolide on cold resistance of Dendrobium huoshanense [J]. Northwest Journal of Botany, 2015, 29 (05):985-990. 5. Li Shuo, Zhang Yi, Yao Qi, etc. Effects of BR on growth and osmotic adjustment characteristics of tomato under isotonic salt stress [J]. Journal of Northwest Sci-Tech University of Agriculture and Forestry (Natural Science Edition), 2020, 048(004):130-136,145. 6. Zheng Liwei, Ma Juanjuan, Zhang Dong, etc. Cloning and expression analysis of T337 MdCBB1 gene in Apple dwarf rootstock [J]. Northwest Journal of Agricultural Sciences, 2016, 25(9):1365-1370. 7. [IF = 4.183] Yukun Chen et al."Seed-Specific Gene MOTHER of FT and TFL1 (MFT) Involved in Embryogenesis, Hormones and Stress Responses in Dimocarpus longan Lour.."Int J Mol Sci. 2018 Aug;19(8):2403 8. [IF=5.279] Shenghuai Hou et al."Boronic Acid-Functionalized Scholl-Coupling Mesoporous Polymers for Online Solid-Phase Extraction of Brassinosteroids from Plant-Derived Foodstuffs."J Agr Food Chem. 2021;69(16):4883-4893 |
epibrassinolide - Nature
Open Data Verified Data
- appearance is white crystal, melting point 185~190 ° C., water solubility of 5 mg/kg, soluble in ethanol and chloroform, acetone and other organic solvents.
- dosage form single dose has 0. 0002%, 0.1% brassinolide soluble powder, 0. 01%, 0.15% brassinolide EC, 0. 0016%, 0.003%, 0. 004%, 0.0075%, 0.01%, 0.04% brassinolide agent; Compound preparation has 0. 751% olefinic action · Brassica water agent, 0. 4% Chi-Yun water agent, 30% Yi-li-Yun water agent, 0. 136% erythroid and indyi-Yun wettable powder.
Last Update：2024-01-02 23:10:35
epibrassinolide - Preparation Method
Open Data Verified Data
can be extracted from rape pollen, now mainly by chemical synthesis.
Last Update：2022-01-01 11:19:03
epibrassinolide - Application
Open Data Verified Data
plant growth regulators can promote crop growth, increase fruit percentage, promote fruit hypertrophy, improve cold tolerance of crops, reduce Phytotoxicity and enhance disease resistance. Brassinolide usually exhibits strong physiological activity at 10 -1 to 10 -5mg/L. Can be used for rice, wheat, barley, corn, potato, radish, lettuce, bean, green pepper, watermelon, grape and other crops.
Last Update：2025-08-19 16:24:40
epibrassinolide - Safety
Open Data Verified Data
low toxicity to humans and animals, mice acute oral LD50>800mg/kg, acute percutaneous LD50>lOOOmg/kg.
Polyethylene bottles of 5ml, 50ml, lOOmL, 200ml and 250ml were tightly arranged in corrugated paper boxes, and the net content of each box was 10L. Packages should be stored in a ventilated, dry warehouse. During storage and transportation, strictly prevent moisture and sun exposure, do not mix with food, seeds and feed, avoid contact with skin and eyes, and prevent inhalation from mouth and nose.
Last Update：2022-01-01 11:19:04
epibrassinolide - Reference Information
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| effect | propionyl brassinolide, also known as propionyl brassinolide, is a plant growth regulator. Propionyl brassinolide is extremely effective on root crops, potatoes and potatoes, grains, corn, cotton, fruits and vegetables, legumes, leafy vegetables, fruit trees, woody plants, flowering plants and economic crops. |
| preparation | 2.06g(3.70mmol) of 2α,3 α-dipropionyloxy-24s-ethyl-5 α-cholestere-22-en-6-one (V) was dissolved in 100ml of dichloromethane, 8.0g(31.08mmol) of M-chloroperoxybenzoic acid was added and the mixture was stirred at room temperature for 15 days. 8.0g of powdered calcium hydroxide were then added, stirred for 1 hour and filtered, the solvent was removed by vacuum distillation and the crude product was obtained. The crude product was refined by silica gel column chromatography (benzene: ethyl acetate 30: 1 to 15: 1) to obtain 0.85g(39.0%) of (22R,23R,24s)-2α,3 α-dipropionyloxy -22,23-epoxy-B-homo-7-oxa-5 α-stigmastane -6-one [compound (I)], (1R,3aS,3bS,6aS,8S,9R,10aR,10bS,12aS)-1-[(1S)-1-[(2R,3R)-3-[(1S)-1-ethyl-2-methylpropyl]-2-oxiranyl] ethyl] hexadecyl-10a, 12a-dimethyl-8, 9-bis (1-oxopropoxy)-6h-benzo [c] indeno [5,4-e] oxa-6-one] is also propionyl brassinolide. |
| biological activity | epibrassinalone is an brassinosteroid that can be isolated from a variety of plants to reduce toxicity, stimulate the healthy growth of plants in response to stress. |
| Target | Plant growth regulator, apotosis inducer |
| Application | is a broad-spectrum and high-efficiency plant growth regulator, which can significantly increase the yield of various economic crops, can effectively regulate the various aspects of plant growth |
| category | pesticide |
| toxicity grade | poisoning |
| Acute toxicity | oral-rat LD50: 2000 mg/kg; Oral-mouse LD50: 1000 mg/kg |
| flammability hazard characteristics | combustion decomposition discharges spicy and irritating smoke |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; It is stored and transported separately from food raw materials |
| extinguishing agent | dry powder, foam, sand |
Last Update：2024-04-09 20:52:54
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