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monotropein

monotropein

CAS: 5945-50-6

Molecular Formula: C16H22O11

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monotropein - Names and Identifiers

Name monotropein
Synonyms Monotropein
monotropein
Monotropeine
Morinda officinalis How
1α-(β-D-Glucopyranosyloxy)-1,4aα,7,7aα-tetrahydro-7β-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid
(1S,4aS,7R,7aS)-1-(hexopyranosyloxy)-7-hydroxy-7-(hydroxymethyl)-1,4a,7,7a-tetrahydrocyclopenta[c]pyran-4-carboxylic acid
(1S,4aS,7R,7aS)-1-(beta-D-Glucopyranosyloxy)-7-hydroxy-7-(hydroxymethyl)-1,4a,7,7a-tetrahydrocyclopenta[c]pyran-4-carboxylic acid
Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,7,7a-tetrahydro-7-hydroxy-7-(hydroxymethyl)-, (1S,4aS,7R,7aS)-
cyclopenta[c]pyran-4-carboxylic acid, 1-(beta-D-glucopyranosyloxy)-1,4a,7,7a-tetrahydro-7-hydroxy-7-(hydroxymethyl)-, (1S,4aS,7R,7aS)-
(1S,2S,6S,9R)-9-hydroxy-9-(hydroxymethyl)-2-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-oxabicyclo[4.3.0]nona-4,7-diene-5-carboxylic acid
(1S,2S,6S,9R)-9-Hydroxy-9-(Hydroxymethyl)-2-[(2S,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxy-3-Oxabicyclo[4.3.0]Nona-4,7-Diene-5-Carboxylic Acid
CAS 5945-50-6
InChI InChI=1/C16H22O11/c17-3-8-10(19)11(20)12(21)15(26-8)27-14-9-6(1-2-16(9,24)5-18)7(4-25-14)13(22)23/h1-2,4,6,8-12,14-15,17-21,24H,3,5H2,(H,22,23)/t6-,8?,9-,10?,11?,12?,14+,15?,16+/m1/s1

monotropein - Physico-chemical Properties

Molecular FormulaC16H22O11
Molar Mass390.34
Density1.73±0.1 g/cm3(Predicted)
Melting Point170-173 °C
Boling Point717.6±60.0 °C(Predicted)
Specific Rotation(α)-129.2°(C=1.00,water)
Flash Point262°C
Solubility Soluble in water and ethanol, almost insoluble in ethyl acetate.
Vapor Presure8.68E-24mmHg at 25°C
AppearanceMonohydrate, colorless needle or columnar crystals (water)
pKa4.31±0.60(Predicted)
Storage ConditionSealed in dry,Store in freezer, under -20°C
Refractive Index1.685
MDLMFCD00238650
Physical and Chemical PropertiesWhite crystalline powder, soluble in water and methanol, derived from Cerola and Morinda officinalis.

monotropein - Risk and Safety

Safety Description24/25 - Avoid contact with skin and eyes.
HS Code29389090

monotropein - Reference

Reference
Show more
1. Wang Feng, Sun Junshe, Hu Shaofeng, et al. Optimization of processing technology of Morinda officinalis how and analysis of changes of effective components [J]. China Brewing, 2015, 34(008):101-105.
2. Zhao Min, Wu Lang, an Jinshuang, etc. Study on quality standard of pyrola formula granules [J]. Chinese traditional Patent Medicine, 2013(01):148-150.
3. Feng Hongyao, Zeng Lingjie, Huang Han, Mo Yuncai, Zhang Xiu-qing, Liang Zhang, Liao Su-Xi, Guo Yu-Mei. Distribution and accumulation of methyl isoalizarin, Crystal lanoside and polysaccharide in root, stem and leaf of Morinda officinalis how [J]. West China Pharmaceutical Journal, 2017,32(02):208-210.
4. Shen Yu, he Yuqiong, Zhang Qi, Liu mengqin, Xinhai, Zhang Quan-long, Qin Lu-ping, Zhang Qiaoyan. Preparation of iridoid glycosides from Morinda officinalis how and their inhibitory effect on bone resorption of osteoclasts [J]. Academic Journal of Second Military Medical University, 2019,40(02):149-156.
5. Fan xiaulong, Chen Ran, Wu Wanqin, Liu Guoyan, Huang Kun, Jiang Feng. Determination of 20 functional components in food by liquid chromatography tandem mass spectrometry [J]. Food and machinery, 2021,37(01):86-93 98.
6. Xu, Wumu, et al. "Bajitianwan attenuates D-galactose-induced memory impact and bone loss through suppression of oxidatatable stress in aging rat model." Journal of Ethnopharmacology 261 (2020): 112992.https://doi.org/10.1016/j.jep.2020.112992
7. [IF=3.659] Shen Yi et al."Pharmacokinetics and tissue distribution of monotropein and deacetyl asperulosidic acid after oral administration of extracts from Morinda officinalis root in rats."Bmc Complem Altern M. 2018 Dec;18(1):1-12
8. [IF=3.69] Wumu Xu et al."Bajitianwan attenuates D-galactose-induced memory impairment and bone loss through suppression of oxidative stress in aging rat model."J Ethnopharmacol. 2020 Oct;261:112992
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