中文名 | 草酸萘呋胺 |
英文名 | nafronyl oxalate |
别名 | 萘呋胺酯 草酸萘呋胺 草酸萘呋胺氢 萘呋胺酯草酸盐 萘呋胺酯草酸盐 标准品 Α-(1-萘基甲基)-2-四氢呋喃丙酸二乙氨基乙酯 Α-(1-萘甲基)-2-四氢呋喃丙酸二乙胺基乙基酯草酸盐 alpha-(1-萘甲基)-2-四氢呋喃丙酸二乙胺基乙基酯草酸盐 |
英文别名 | ls121 eu-1806 CLARANTIN nafronyl oxalate naftidrofuryloxalate Nafronyl acid oxalate Naftidrofuryl oxalate naftidrofuryl hydrogen oxalate 2-(diethylamino)ethyltetrahydro-alpha-(1-naphthylmethyl)-2-furanpropionateo 2-(diethylamino)ethyl 3-(naphthalen-1-yl)-2-(tetrahydrofuran-2-ylmethyl)propanoate alpha-(1-Naphthylmethyl)-2-tetrahydrofuranpropionic acid diethylaminoethyl ester oxalate diethyl-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoyl]oxyethyl]ammonium, oxalate diethyl[2-[2-(1-naphthylmethyl)-3-(tetrahydro-2-furyl)propionyloxy]ethyl]ammonium hydrogen oxalate |
CAS | 3200-06-4 |
EINECS | 221-703-0 |
化学式 | C26H35NO7 |
分子量 | 473.56 |
InChI | InChI=1/C24H33NO3.C2H2O4/c1-3-25(4-2)14-16-28-24(26)21(18-22-12-8-15-27-22)17-20-11-7-10-19-9-5-6-13-23(19)20;3-1(4)2(5)6/h5-7,9-11,13,21-22H,3-4,8,12,14-18H2,1-2H3;(H,3,4)(H,5,6)/p-1 |
密度 | 1.2205 (rough estimate) |
熔点 | 110-111° |
沸点 | 574°C (rough estimate) |
闪点 | 355.6°C |
蒸汽压 | 1.48E-18mmHg at 25°C |
溶解度 | 易溶于水,易溶于或溶于乙醇 (96%),微溶于或微溶于丙酮。 |
折射率 | 1.6000 (estimate) |
存储条件 | 2-8℃ |
体外研究 | Naftidrofuryl oxalate (Nafronyl oxalate salt) may be effective for relieving the pain of muscle cramps. Naftidrofuryl oxalate (Nafronyl oxalate salt) is the only vasoactive drug for peripheral arterial disease (PAD) which is likely to be cost-effective. Naftidrofuryl oxalate (Nafronyl oxalate salt) is ranked first for both maximum walking distance (MWD) and pain-free walking distance (PFWD) (probability of 0·947 and 0·987, respectively, of being the best treatment) followed by cilostazol and pentoxifylline. Naftidrofuryl oxalate (Nafronyl oxalate salt) is effective treatments for claudication, Naftidrofuryl oxalate is likely to be the most effective, with minimal serious adverse events. |
危险品标志 | Xn - 有害物品 Xi - 刺激性物品 |
风险术语 | 22 - 吞食有害。 |
安全术语 | 36 - 穿戴适当的防护服。 |
WGK Germany | 3 |
RTECS | LU5805000 |
海关编号 | 29321900 |
上游原料 | 乙醇 盐酸 二氯甲烷 甲苯 丙酮 乙醇钠 草酸 二乙氨基乙醇 2-溴甲基四氢呋喃 |
下游产品 | 萘呋胺酯 |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.112 ml | 10.558 ml | 21.117 ml |
5 mM | 0.422 ml | 2.112 ml | 4.223 ml |
10 mM | 0.211 ml | 1.056 ml | 2.112 ml |
5 mM | 0.042 ml | 0.211 ml | 0.422 ml |
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