(2S,4E)-5-(5-异丙基吡啶-3-)-N-甲基戊-4-烯-2-胺

中文名	Ispronicline
英文名	Ispronicline
别名	化合物 T27636 (2S,4E)-5-(5-异丙基吡啶-3-)-N-甲基戊-4-烯-2-胺
英文别名	ispronicline Ispronicline Ispronicline (TC-1734 AZD-3480) galactaric acid salt Ispronicline(TC-1734, AZD-3480) (2S,4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine (2S,4E)-5-(5-isopropoxypyridin-3-yl)-N-Methylpent-4-en-2-aMine (E,2S)-N-methyl-5-(5-propan-2-yloxypyridin-3-yl)pent-4-en-2-amine Ispronicline, (2S,4E)-5-(5-isopropoxypyridin-3-yl)-N-Methylpent-4-en-2-aMine
CAS	252870-53-4
化学式	C14H22N2O
分子量	234.34
密度	0.977±0.06 g/cm3(Predicted)
沸点	bp0.5 90-100°
酸度系数	10.03±0.10(Predicted)
存储条件	-20℃
产品用途	Ispronicline, also known as AZD3480; TC 1734; TC-0173, and RJR 1734, is a alpha4beta2 nicotinic acetylcholine receptor-selective agonist with cognition-enhancing and neuroprotective properties. Ispronicline is potentially useful for the treatment of attention-deficit/hyperactivity disorder in adults.
参考资料展开查看	1: Buoli M, Serati M, Cahn W. Alternative pharmacological strategies for adult ADHD treatment: a systematic review. Expert Rev Neurother. 2016;16(2):131-44. doi: 10.1586/14737175.2016.1135735. Review. PubMed PMID: 26693882. 2: Gabrielsson J, Peletier LA. Dose-response-time data analysis involving nonlinear dynamics, feedback and delay. Eur J Pharm Sci. 2014 Aug 1;59:36-48. doi: 10.1016/j.ejps.2014.04.007. PubMed PMID: 24751673. 3: Levin ED. Nicotinic attention-deficit/hyperactivity disorder treatment. Biol Psychiatry. 2014 Feb 1;75(3):174. doi: 10.1016/j.biopsych.2013.11.024. PubMed PMID: 24370349. 4: Potter AS, Dunbar G, Mazzulla E, Hosford D, Newhouse PA. AZD3480, a novel nicotinic receptor agonist, for the treatment of attention-deficit/hyperactivity disorder in adults. Biol Psychiatry. 2014 Feb 1;75(3):207-14. doi: 10.1016/j.biopsych.2013.06.002. PubMed PMID: 23856296. 5: Rezvani AH, Cauley MC, Johnson EC, Gatto GJ, Levin ED. Effects of AZD3480, a neuronal nicotinic acetylcholine receptor agonist, and donepezil on dizocilpine-induced attentional impairment in rats. Psychopharmacology (Berl). 2012 Oct;223(3):251-8. doi: 10.1007/s00213-012-2712-2. PubMed PMID: 22526540. 6: Jacobsen J, Hansen HH, Kiss A, Mikkelsen JD. The α4β2 nicotine acetylcholine receptor agonist ispronicline induces c-Fos expression in selective regions of the rat forebrain. Neurosci Lett. 2012 Apr 25;515(1):7-11. doi: 10.1016/j.neulet.2012.02.081. PubMed PMID: 22414858.

(2S,4E)-5-(5-异丙基吡啶-3-)-N-甲基戊-4-烯-2-胺 - 配置溶液浓度参考

	1mg	5mg	10mg
1 mM	4.267 ml	21.336 ml	42.673 ml
5 mM	0.853 ml	4.267 ml	8.535 ml
10 mM	0.427 ml	2.134 ml	4.267 ml
5 mM	0.085 ml	0.427 ml	0.853 ml

最后更新：2024-01-02 23:10:35

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产品名: Ispronicline 去供应商网站查看询盘
CAS: 252870-53-4
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产品名: (2S,4E)-5-(5-异丙基吡啶-3-)-N-甲基戊-4-烯-2-胺去供应商网站查看询盘
CAS: 252870-53-4
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产品名: Ispronicline 去供应商网站查看询盘
CAS: 252870-53-4
产地: 上海
规格: 98%
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