中文名 | MLS000544460 |
英文名 | MLS000544460 |
别名 | 化合物 T12080 |
英文别名 | MLS000544460 |
CAS | 352336-36-8 |
化学式 | C17H12FN3O2S |
分子量 | 341.36 |
存储条件 | 2-8°C,干燥,密封 |
体外研究 | MLS000544460 does not bind Eya3 phosphatase (ED). MLS000544460 (10 μM) inhibits Eya2-mediated cell migration in human Eya2, Eya2 phosphatase-dead (D274N), and YFP (as a negative control) expressing MCF10A cells. When Eya2 ED is dialyzed into 10 μM EDTA to remove Mg 2+ , it binds MLS000544460 with a higher affinity (K d =0.80 μM), indicating that this class of compounds does not require Mg 2+ for its interaction with the Eya2 ED. |
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