中文名 | 托洛尼定 |
英文名 | tolonidine |
别名 | 托洛尼定 化合物 T17113 |
英文别名 | ST-375 tolonidine N-(2-Chloro-4-methylphenyl)-4,5-dihydro-1H-imidazol-2-amine |
CAS | 4201-22-3 |
化学式 | C10H12ClN3 |
分子量 | 209.68 |
熔点 | 148-150° |
酸度系数 | 9.41(at 25℃) |
体内研究 | In the anesthetized dog, tolonidine administered i.v. decreases the amplitude of ventricular contractions, reduces aortic blood flow and increases peripheral vascular resistances. In the bivagotomized pithed rat, tolonidine induces a long-lasting increase in blood pressure with no secondary hypotension, thus suggesting peripheral sympathomimetic properties. |
上游原料 | 乙二胺 硝酸 |
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