N-(1-azabicyclo(2.2.2)octan-3-yl)-2-chloro-5a,6,7,8,9,9a-hexahydrodibenzofuran-4-carboxamide

中文名	N-(1-azabicyclo(2.2.2)octan-3-yl)-2-chloro-5a,6,7,8,9,9a-hexahydrodibenzofuran-4-carboxamide
英文名	N-(1-azabicyclo(2.2.2)octan-3-yl)-2-chloro-5a,6,7,8,9,9a-hexahydrodibenzofuran-4-carboxamide
别名	化合物 T12716
英文别名	N-(1-azabicyclo(2.2.2)octan-3-yl)-2-chloro-5a,6,7,8,9,9a-hexahydrodibenzofuran-4-carboxamide 4-Dibenzofurancarboxamide, N-(3S)-1-azabicyclo(2.2.2)oct-3-yl-2-chloro-5A,6,7,8,9,9A-hexahydro-, (5as,9as)- 4-Dibenzofurancarboxamide, N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-2-chloro-5a,6,7,8,9,9a-hexahydro-, (5aS,9aS)- (9CI) (5As-(4(R),5aalpha,9aalpha))-N-1-azabicyclo(2.2.2)oct-3-yl-2-chloro-5A,6,7,8,9,9A-hexahydro-4-dibenzofurancarboxamide 4-Dibenzofurancarboxamide, N-1-azabicyclo(2.2.2)oct-3-yl-2-chloro-5A,6,7,8,9,9A-hexahydro-, (5as-(4(R),5aalpha,9aalpha))-
CAS	136174-04-4
化学式	C20H25ClN2O2
分子量	360.88
密度	1.31±0.1 g/cm3(Predicted)
沸点	462.6±45.0 °C(Predicted)
酸度系数	13.83±0.20(Predicted)
存储条件	Room Temprature
体外研究	RG 12915 is a potent and selective displacer of binding of 5-hydroxytryptamine (5-HT3) binding sites (IC 50 value = 0.16 nM), whereas failing to displace binding of ligands for the alpha-1, alpha-2 and beta adrenergic, 5-HT1 or 5-HT2 or cholinergic-muscarinic sites with IC 50 values less than 1 μM.
体内研究	RG 12915 has a lower ED 50 value (0.004 mg/kg) for attenuating cisplatin-induced emetic episodes in the ferret. RG 12915 (1 mg/kg, p.o.) is highly protective against cisplatin-induced emesis in the dog. RG 12915 has no significant gastroprokinetic activity in the same species.

N-(1-azabicyclo(2.2.2)octan-3-yl)-2-chloro-5a,6,7,8,9,9a-hexahydrodibenzofuran-4-carboxamide - 简介

N-(1-azabicyclo(2.2.2)octan-3-yl)-2-chloro-5a,6,7,8,9,9a-hexahydrodibenzofuran-4-carboxamide是一种有机化合物。以下是它的性质，用途，制法和安全信息的介绍：

性质：
- 外观：这种化合物可能以固体或液体形式存在。
- 溶解性：它可能在某些有机溶剂中可溶，如氯仿或二氯甲烷。

用途：
- 它可能具有一定的生物活性，可能用于生物医学研究。

制法：

安全信息：

最后更新：2024-04-09 20:49:11

上海麦克林生化科技股份有限公司

现货供应

产品名: RG-12915 去供应商网站查看询盘
CAS: 136174-04-4
产地: 上海
规格: R882980
价格: 5mg-17755,1mg-8920
库存: 15天内发货
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上海源叶生物科技有限公司

产品名: N-(1-azabicyclo(2.2.2)octan-3-yl)-2-chloro-5a,6,7,8,9,9a-hexahydrodibenzofuran-4-carboxamide 去供应商网站查看询盘
CAS: 136174-04-4
产地: 上海
规格: 98%
价格: 1mg 12450,5mg 24780
电话: 18301782025
手机: 18301782025
电子邮件: 3008007403@qq.com
QQ: 3008007403

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产品描述: N-(1-azabicyclo(2.2.2)octan-3-yl)-2-chloro-5a,6,7,8,9,9a-hexahydrodibenzofuran-4 更多

上海麦克林生化科技股份有限公司

现货供应

微信: 19863730987/17821173903

上海源叶生物科技有限公司

微信: 18301782025
产品描述: N-(1-azabicyclo(2.2.2)octan-3-yl)-2-chloro-5a,6,7,8,9,9a-hexahydrodibenzofuran-4 更多

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