STAT5抑制剂(STAT5-IN-1)
STAT5-IN-1(STAT5-IN-1)
CAS: 285986-31-4
化学式: C16H11N3O3
| 中文名 | STAT5-IN-1 |
| 英文名 | STAT5-IN-1 |
| 别名 | STAT5抑制剂 化合物STAT5 INHIBITOR STAT5抑制剂(STAT5-IN-1) |
| 英文别名 | MDK6314 CS-2509 STAT5-IN-1 STAT5 Inhibitor STAT5 Inhibitor 1 N'-[(4-oxo-4H-chromen-3-yl)methylene]nicotinohydrazide (E)-N'-((4-oxo-4H-chromen-3-yl)methylene)nicotinohydrazide 3-Pyridinecarboxylic acid, 2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazide |
| CAS | 285986-31-4 |
| EINECS | 604-604-1 |
| 化学式 | C16H11N3O3 |
| 分子量 | 293.28 |
| 密度 | 1.33±0.1 g/cm3(Predicted) |
| 熔点 | 214-216 °C |
| 溶解度 | DMSO: ≥ 23.0 mg/mL |
| 酸度系数 | 10.44±0.46(Predicted) |
| 存储条件 | 2-8°C(protect from light) |
| 体外研究 | The signal transducer and activator of transcription 5 (STAT5) is a member of the STAT family of proteins, implicated in cell growth and differentiation. STAT5-IN-1 inhibits STAT5 by binding to the SH2 domain. The functions of the SH2 domains of STAT3, STAT1, and of the tyrosine kinase Lck are inhibited to a lesser extent (IC50>500 µM). STAT5-IN-1 block STAT5/STAT5 DNA binding in K562 nuclear extracts. Substitution of the hydrogen at C6 of the chromone ring by an ethyl group does not affect activity of STAT5-IN-1 against STAT5β, but leads to complete loss of selectivity against other STAT family members. |
STAT5抑制剂(STAT5-IN-1) - 配置溶液浓度参考
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.41 ml | 17.049 ml | 34.097 ml |
| 5 mM | 0.682 ml | 3.41 ml | 6.819 ml |
| 10 mM | 0.341 ml | 1.705 ml | 3.41 ml |
| 5 mM | 0.068 ml | 0.341 ml | 0.682 ml |
最后更新：2024-01-02 23:10:35
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现货供应
产品名: STAT5-IN-1 去供应商网站查看 询盘CAS: 285986-31-4
产地: 上海
规格: S879818
价格: 5mg-354,25mg-851,100mg-2627,1ml-251
库存: 现货
电话: 13816333479/13918391375
手机: 13816333479/13918391375
电子邮件: wangrui@macklin.cn
QQ: 2885703204/285395191
微信: 19863730987/13918391375
现货供应
产品名: STAT5-IN-1 去供应商网站查看 询盘CAS: 285986-31-4
产地: 上海
规格: 98%
价格: 2mg 200,5mg 320,10mg 560,25mg 1200,50mg 2240,100mg 4400
库存: 现货
电话: 18301782025
手机: 18301782025
电子邮件: 3008007403@qq.com
QQ: 3008007403
微信: 18301782025
产品描述: STAT5-IN-1 98% MedMol 货号：S84762
现货供应
产品名: STAT5-IN-1 去供应商网站查看 询盘CAS: 285986-31-4
产地: 上海
规格: S879818
价格: 5mg-354,25mg-851,100mg-2627,1ml-251
库存: 现货
电话: 13816333479/13918391375
手机: 13816333479/13918391375
电子邮件: wangrui@macklin.cn
QQ: 2885703204/285395191
微信: 19863730987/13918391375
现货供应
产品名: STAT5-IN-1 去供应商网站查看 询盘CAS: 285986-31-4
产地: 上海
规格: 98%
价格: 2mg 200,5mg 320,10mg 560,25mg 1200,50mg 2240,100mg 4400
库存: 现货
电话: 18301782025
手机: 18301782025
电子邮件: 3008007403@qq.com
QQ: 3008007403
微信: 18301782025
产品描述: STAT5-IN-1 98% MedMol 货号：S84762
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