中文名 | 刺蒺藜苷 |
英文名 | tiliroside |
别名 | 银椴苷 银锻苷 银椴甙 椴树苷 密蒙花苷 刺蒺藜苷 银锻苷,椴树苷 椴树苷,密蒙花苷 椴树苷(分析标准品) |
英文别名 | tiliroside TILIROSIDE 20316-62-5 6''-O-trans-p-CouMaroylastragalin KAEMPFEROL-3-(P-COUMARYL)GLUCOSIDE Kaempferol 3-O-β-D-(6?″-O-(E)-p-coumaroyl)glucopyranoside xy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one 3-(4-hydroxyphenyl)-2-propenoicaci6'-esterwith3-(beta-d-glucopyranosylo 2-(4-Hydroxyphenyl)-3-[6-O-[3-(4-hydroxyphenyl)acryloyl]-β-D-glucopyranosyloxy]-5,7-dihydroxy-4H-1-benzopyran-4-one 1-O-[5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-3-yl]-β-D-glucopyranose 6-[3-(4-hydroxyphenyl)propenoate] 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-O-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-b-D-glucopyranoside 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl-6-O-[(2E)-3-(4-hydroxyphenyl)-2-propenoyl]-beta-D-glucopyranoside 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-O-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-beta-D-glucopyranoside 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-O-[(2E)-3-(4-hydroxyphenyl)-2-propenoyl]-beta-D-glucopyranoside 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[[6-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-.beta.-D-glucopyranosyl]oxy]- [(2R,3S,4S,5R,6S)-6-{[5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl]oxy}-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]methyl-(2E)-3-(4-hydroxyphenyl)acrylat [(2R,3S,4S,5R,6S)-6-{[5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl]oxy}-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]methyl (2E)-3-(4-hydroxyphenyl)acrylate (2E)-3-(4-Hydroxyphényl)acrylate de [(2R,3S,4S,5R,6S)-6-{[5,7-dihydroxy-2-(4-hydroxyphényl)-4-oxo-4H-chromén-3-yl]oxy}-3,4,5-trihydroxytétrahydro-2H-pyran-2-yl]méthyle |
CAS | 20316-62-5 |
化学式 | C30H26O13 |
分子量 | 594.52 |
InChI | InChI=1/C30H26O13/c31-16-6-1-14(2-7-16)3-10-22(35)40-13-21-24(36)26(38)27(39)30(42-21)43-29-25(37)23-19(34)11-18(33)12-20(23)41-28(29)15-4-8-17(32)9-5-15/h1-12,21,24,26-27,30-34,36,38-39H,13H2/b10-3+/t21-,24-,26+,27-,30+/m1/s1 |
密度 | 1.68±0.1 g/cm3(Predicted) |
熔点 | 257-260°C |
沸点 | 943.9±65.0 °C(Predicted) |
比旋光度 | -62 (c, 0.28 in MeOH) |
闪点 | 311℃ |
蒸汽压 | 0mmHg at 25°C |
溶解度 | 可溶于甲醇、DMSO等有机溶剂,不溶于石油醚、氯仿、乙醚等。 |
折射率 | 1.758 |
酸度系数 | 6.20±0.40(Predicted) |
存储条件 | Keep in dark place,Inert atmosphere,2-8°C |
外观 | 整洁 |
物化性质 | 白色结晶粉末,可溶于甲醇、乙醇、DMSO等有机溶剂,来源于华东覆盆子。 |
MDL号 | MFCD00017454 |
体外研究 | Tiliroside inhibits pancreatic α-amylase (IC 50 =0.28 mM) in vitro. |
体内研究 | In male ICR mice, the increase in postprandial plasma glucose levels was significantly suppressed in the Tiliroside-administered group. |
WGK Germany | 3 |
海关编号 | 29389090 |
参考资料 展开查看 | 1. 仲维兰. 银椴苷抑制人胰腺癌细胞增殖的作用及机制研究[J]. 中国药理学通报, v.34(12):1679-1683. 2. 姚鑫,诸炜荣,黄宏亮,曾燕如,喻卫武.掌叶覆盆子药用有效成分变异与优良种质筛选[J].中国中药杂志,2021,46(03):575-581. 3. Wang, Xu, et al. "Molecular basis of rutin inhibition of protein disulfide isomerase (PDI) by combined in silico and experimental methods." RSC advances 8.33 (2018): 18480-18491.DOI: 10.1039/C8RA02683A 4. Guang Yang, Xin Zhao, Guorong Fan,A modification on the vector cosine algorithm of Similarity Analysis for improved discriminative capacity and its application to the quality control of Magnoliae Flos,Journal of Chromatography A,Volume 1518,2017,Pages 5. [IF=4.759] Guang Yang et al."A modification on the vector cosine algorithm of Similarity Analysis for improved discriminative capacity and its application to the quality control of Magnoliae Flos."J Chromatogr A. 2017 Oct;1518:34 6. [IF=3.049] Xu Wang et al."Molecular basis of rutin inhibition of protein disulfide isomerase (PDI) by combined in silico and experimental methods."Rsc Adv. 2018 May;8(33):18480-18491 7. [IF=9.229] Linlin Deng et al."Highly Crystalline Covalent Organic Frameworks Act as a Dual-Functional Fluorescent-Sensing Platform for Myricetin and Water, and Adsorbents for Myricetin."Acs Appl Mater Inter. 2021;13(28):33449–33463 8. [IF=5.279] Qiangqiang Li et al."Extract of Unifloral Camellia sinensis L. Pollen Collected by Apis mellifera L. Honeybees Exerted Inhibitory Effects on Glucose Uptake and Transport by Interacting with Glucose Transporters in Human Intestinal Cells."J Agr Food Chem. |
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