中文名 | 贝母甲素 |
英文名 | Peimine |
别名 | 貝母鹼 浙贝甲素 贝母甲素 浙贝母碱 贝母素甲 浙)贝母甲素 贝母素甲(标准品) 贝母素甲,浙贝甲素 |
英文别名 | PEIMINE Peimine Verticin Verticine VERTICINE PAYNANTHEINE(SH) ISODIHYDROIMPERIALINE Dihydroisoimperialine (5α)-Cevane-3β,6α,20-triol Cevane-3,6,20-triol, (3β,5α,6α)- (3beta,5alpha,6alpha)-cevane-3,6,20-triol |
CAS | 23496-41-5 |
化学式 | C27H45NO3 |
分子量 | 431.66 |
InChI | InChI=1/C27H45NO3/c1-15-4-7-25-27(3,31)21-6-5-17-18(20(21)14-28(25)13-15)11-22-19(17)12-24(30)23-10-16(29)8-9-26(22,23)2/h15-25,29-31H,4-14H2,1-3H3/t15-,16-,17+,18+,19-,20-,21-,22-,23+,24-,25-,26+,27-/m0/s1 |
密度 | 1.18±0.1 g/cm3(Predicted) |
熔点 | 223-224° |
沸点 | 568.4±50.0 °C(Predicted) |
比旋光度 | D16 -19.4° (ethanol); D17 -20° (CHCl3) |
闪点 | 275.3°C |
蒸汽压 | 2.74E-15mmHg at 25°C |
溶解度 | 乙腈 (微溶,加热,超声处理),氯仿 (微溶),乙醇 (Slig |
折射率 | 1.591 |
酸度系数 | 9.5(at 25℃) |
存储条件 | under inert gas (nitrogen or Argon) at 2–8 °C |
外观 | 固体 |
颜色 | White to Off-White |
物化性质 | 白色结晶,溶于氯仿,来源于浙贝母Fritillaria thunbergii。 |
MDL号 | MFCD02259442 |
安全术语 | 24/25 - 避免与皮肤和眼睛接触。 |
海关编号 | 29420000 |
参考资料 展开查看 | 1. 雨田, 练心洁, 孙佑玲,等. 浙贝母原产地及其迁地引种后含量分析[J]. 成都大学学报(自然科学版), 2018, 37(04):36-38+49. 2. 王又迪,申屠瑞莎,潘颖洁,梁泽华.以浙贝母为例研究硫熏炮制新工艺[J].山东中医药大学学报,2020,44(05):576-579. 3. 乌晓.HPLC-ELSD法测定诱变育种后浙贝母生物碱活性成分的研究[J].人参研究,2020,32(05):43-46. 4. 程斌,周爱珍,彭昕,王昕蕾,王娟.浙贝母UPLC-Q-TOF-MS/MS指纹图谱的建立及其抗炎质量标志物的分析[J].中国药房,2020,31(17):2129-2135. 5. [IF=3.373] Issac Chi-Chung Cheng et al."Application of UPLC-MS/MS to simultaneously detect four bioactive compounds in the tumour-shrinking decoction (FM1523) for uterine fibroids treatment."Phytochem Analysis. 2019 Jul;30(4):447-455 6. [IF=5.645] Ning Sui et al."Estimating Fritillaria thunbergii Miq. yield, quality, and potassium use efficiency in response to potassium application rate."Ind Crop Prod. 2021 Jun;164:113409 7. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950 8. [IF=2.289] Zhou Shun et al."Anthelmintic efficacy of natural saponins against Gyrodactylus kobayashii in goldfish (Carassius auratus) and their 3D-QSAR analysis."Parasitol Res. 2021 Mar;120(3):1143-1150 9. [IF=5.34] Dong Shao et al."Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology."PHYTOMEDICINE. 2022 Jul;102:154177 |
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