中文名 | 紫杉叶素 |
英文名 | (+-)-taxifolin |
别名 | 黄杉素 花旗松素 紫杉叶素 花旗松素(标准品) 二氢槲皮素,紫杉叶素 花旗松素(二氢槲皮素) (2R,3R)-二氢槲皮素 花旗松素,二氢槲皮素(标准品) 花旗松素,紫杉叶素,二氢槲皮素 5,7,3',4'-四羟基二氢黄酮醇 |
英文别名 | distylin taxifolin TAXIFOLIN(P) (+-)-taxifolin 2theta-trans)- dihydro-querceti 3,3',4',5,7-pentahydroxy-flavanon 2,3-dihydro-3,3',4',5,7-pentahydroxy-flavon 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4h-1-benzopyran-4-on 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4h-1-benzopyran-4-on( (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydro-4H-chromen-4-one (2S,3S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydro-4H-chromen-4-one |
CAS | 480-18-2 |
EINECS | 207-543-4 |
化学式 | C15H12O7 |
分子量 | 304.25 |
InChI | InChI=1/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H/t14-,15+/m1/s1 |
InChIKey | CXQWRCVTCMQVQX-LSDHHAIUSA-N |
密度 | 1.3326 (rough estimate) |
熔点 | 230-233°C (dec.) |
沸点 | 365.09°C (rough estimate) |
比旋光度 | (c, 1.03 in 50% Me2CO aq.)+44 |
闪点 | 264.1°C |
蒸汽压 | 7.51E-20mmHg at 25°C |
溶解度 | DMSO (微溶) 、甲醇 (微溶) |
折射率 | 1.4790 (estimate) |
酸度系数 | 7.39±0.60(Predicted) |
存储条件 | -20°C |
外观 | 整洁 |
颜色 | White to Yellow |
BRN | 5299277 |
物化性质 | 来源于松科植物花旗松 |
MDL号 | MFCD00006845 |
风险术语 | 22 - 吞食有害。 |
安全术语 | S22 - 切勿吸入粉尘。 S24/25 - 避免与皮肤和眼睛接触。 |
WGK Germany | 3 |
RTECS | LK6920000 |
海关编号 | 29329990 |
Hazard Class | IRRITANT |
下游产品 | 白西尼多 |
参考资料 展开查看 | 1. 顾媛媛 姜波 田明 等. 二氢槲皮素对局灶性脑缺血损伤模型大鼠血液流变学等相关指标的影响[J]. 中国药房 2019年30卷6期 765-769页 ISTIC PKU CA 2019. 2. 尚艳琦 于莹 顾媛媛 等. 二氢槲皮素对心肌缺血大鼠血液流变学相关指标的影响[J]. 长春中医药大学学报 2019 035(003):509-512. 3. 顾媛媛 于莹 周忠光 等. 二氢槲皮素对心肌缺血模型大鼠的保护作用及氧化应激水平的影响[J]. 时珍国医国药 2019 v.30;No.290(10):72-74. 4. 顾媛媛 姜波 刘旭 尚艳琦 梁慧 张淑香 董晓红 周忠光 田明.二氢槲皮素对脑缺血损伤模型大鼠炎症因子、氧化应激水平以及脑组织能量代谢影响[J].辽宁中医药大学学报 2019 21(06):36-38. 5. 宋光兰,陈俊,鲜文.花旗松素通过抑制NF-κB信号通路对缺氧复氧诱导H9c2心肌细胞损伤的保护作用[J].临床和实验医学杂志,2020,19(01):54-58. 6. 吴明娟 费洪新 田明 周忠光 韩玉生.二氢槲皮素对异丙肾上腺素所致急性心肌缺血大鼠心肌磷脂酰肌醇3-激酶/糖原合成酶激酶-3β信号通路的影响[J].中国医药导报 2020 17(02):15-19. 7. 杨俊杰, 黄紫炎, 李林,等. 土茯苓产地加工与炮制一体化工艺优选[J]. 时珍国医国药, 2018, 29(09):2165-2168. 8. 杨俊杰,张艳玲,王峥涛,陆兔林.土茯苓产地加工过程中去皮的合理性分析[J].中国实验方剂学杂志,2017,23(03):1-5. 9. 林丽,李欢欢,谢辉,严国俊,胡玉涛,陆兔林,毛春芹.基于HPLC指纹图谱结合化学计量学的旋覆花药材质量评价研究[J].中草药,2021,52(06):1751-1758. 10. Wu, Ya, et al. "Anti‐obesity effect of Liupao tea extract by modulating lipid metabolism and oxidative stress in high‐fat‐diet‐induced obese mice." Journal of Food Science 86.1 (2021): 215-227. 11. Lyu, Yunbin, et al. "Identification and characterization of three flavonoid 3-O-glycosyltransferases from Epimedium koreanum Nakai." Biochemical Engineering Journal 163 (2020): 107759.https://doi.org/10.1016/j.bej.2020.107759 12. [IF=5.64] Wu Dousheng et al."Oleanolic Acid Induces the Type III Secretion System of Ralstonia solanacearum."Front Microbiol. 2015 Dec;0:1466 13. [IF=4.939] Jinghui Wang et al."Systems Pharmacology Dissection of Multiscale Mechanisms of Action for Herbal Medicines in Treating Rheumatoid Arthritis."Mol Pharmaceut. 2017;14(9):3201–3217 14. [IF=4.411] Xiaosheng Tang et al."Molecular Structure–Affinity Relationship of Flavonoids in Lotus Leaf (Nelumbo nucifera Gaertn.) on Binding to Human Serum Albumin and Bovine Serum Albumin by Spectroscopic Method."Molecules. 2017 Jul;22(7):1036 15. [IF=3.361] Hui Li et al."Enrichment and purification of polyphenols in pine cone extracts of Pinus koraiensis Sieb. et Zucc. using a novel multi-channel parallel–serial chromatographic system packed with macroporous resin."Rsc Adv. 2015 Mar;5(39):30711-30718 16. [IF=9.038] Yingying Zheng et al."Di-(2-ethyl hexyl) phthalate induces necroptosis in chicken cardiomyocytes by triggering calcium overload."J Hazard Mater. 2020 Apr;387:121696 17. [IF=8.071] Jingzeng Cai et al."Taxifolin ameliorates DEHP-induced cardiomyocyte hypertrophy via attenuating mitochondrial dysfunction and glycometabolism disorder in chicken."Environ Pollut. 2019 Dec;255:113155 18. [IF=6.291] Yuan Zhang et al."Taxifolin alleviates apoptotic injury induced by DEHP exposure through cytochrome P450 homeostasis in chicken cardiomyocytes."Ecotox Environ Safe. 2019 Nov;183:109582 19. [IF=5.81] Mu Jianfei et al."Determination of Polyphenols in Ilex kudingcha and Insect Tea (Leaves Altered by Animals) by Ultra-high-performance Liquid Chromatography-Triple Quadrupole Mass Spectrometry (UHPLC-QqQ-MS) and Comparison of Their Anti-Aging Effects."Fro 20. [IF=4.464] Di Huang et al."A new electrochemical sensor for Taxifolin based on RGO-Co3S4@MoS2 modified electrode."J Electroanal Chem. 2019 Oct;851:113473 21. [IF=3.978] Yunbin Lyu et al."Identification and characterization of three flavonoid 3-O-glycosyltransferases from Epimedium koreanum Nakai."Biochem Eng J. 2020 Nov;163:107759 22. [IF=3.645] Qingyu Zhang et al."Quality control of Semen Hoveniae by high-performance liquid chromatography coupled to Fourier transform-ion cyclotron resonance mass spectrometry."J Sep Sci. 2021 Sep;44(18):3366-3375 23. [IF=3.645] Chen Wang et al."Qualitative and quantitative analysis of phenolic compounds in blueberries and protective effects on hydrogen peroxide-induced cell injury."J Sep Sci. 2021 Jul;44(14):2837-2855 24. [IF=3.167] Ya Wu et al."Anti-obesity effect of Liupao tea extract by modulating lipid metabolism and oxidative stress in high-fat-diet-induced obese mice."J Food Sci. 2021 Jan;86(1):215-227 25. [IF=2.19] Sheng-xiang Yang et al."Extraction of flavonoids from Cyclocarya paliurus (Juglandaceae) leaves using ethanol/salt aqueous two-phase system coupled with ultrasonic."J Food Process Pres. 2020 Jun;44(6):e14469 26. [IF=1.296] Han Meiling et al."Analysis of flavonoids and anthocyanin biosynthesis-related genes expression reveals the mechanism of petal color fading of Malus hupehensis (Rosaceae)."Braz J Bot. 2020 Mar;43(1):81-89 27. [IF=3.935] Junmao Li et al."Comprehensive chemical profiling of the flowers of Citrus aurantium L. var. amara Engl. and uncovering the active ingredients of lipid lowering."J Pharmaceut Biomed. 2022 Mar;211:114621 28. [IF=6.576] Junkun Pan et al."Inhibition of Dipeptidyl Peptidase-4 by Flavonoids: Structure–Activity Relationship, Kinetics and Interaction Mechanism."Frontiers in Nutrition. 2022; 9: 892426 |
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