(1S,2S,5S)-(-)-2-hydroxy-3-pinanone
(1S,2S,5S)-(-)-2-hydroxy-3-pinanone
CAS: 1845-25-6
Molecular Formula: C10H16O2
(1S,2S,5S)-(-)-2-hydroxy-3-pinanone - Names and Identifiers
| Name | (1S,2S,5S)-(-)-2-hydroxy-3-pinanone |
| Synonyms | Hydroxypinanone (-)-2a-Hydroxypinocamphone (1S,2S,5S)-(-)-2-HYDROXY-3-PINANONE (1S,2S,5S)-(-)-2-Hydroxy-3-pinanone (1S,2S,5S)-(-)-2-HYDROXYPINAN-3-ONE (1S,2S,5S)-(-)-2-hydroxy-3-pinanone (-)-(1S,2S,5S)-2-HYDROXY-3-PINANONE (2S)-2-hydroxy-2,6,6-trimethyl-norpinan-3-one (1S,2S,5S)-2-HYDROXY-2,6,6-TRIMETHYL-BICYCLO[3.1.1]HEPTAN-3-ONE (1S,2S,5S)-(-)-2-HYDROXY-2,6,6-TRIMETHYLBICYCLO[3.1.1]HEPTAN-3-ONE |
| CAS | 1845-25-6 |
| InChI | InChI=1/C10H16O2/c1-9(2)6-4-7(9)10(3,12)8(11)5-6/h6-7,12H,4-5H2,1-3H3/t6?,7?,10-/m0/s1 |
(1S,2S,5S)-(-)-2-hydroxy-3-pinanone - Physico-chemical Properties
| Molecular Formula | C10H16O2 |
| Molar Mass | 168.23 |
| Density | 1.059 g/mL at 25 °C (lit.) |
| Melting Point | 36-38 °C (lit.) |
| Boling Point | 245 °C (lit.) |
| Flash Point | 224°F |
| Solubility | Chloroform, Ethyl Acetate, Methanol |
| Vapor Presure | 0.00491mmHg at 25°C |
| Appearance | Oil |
| Color | Clear Colorless |
| BRN | 3196635 |
| pKa | 12.93±0.40(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | -33 ° (C=0.5, CHCl3) |
(1S,2S,5S)-(-)-2-hydroxy-3-pinanone - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
(1S,2S,5S)-(-)-2-hydroxy-3-pinanone - Introduction
(1S,2S,5S)-(-)-2-hydroxy-3-pinanone, chemical name is (1S,2S,5S)-( )-2-hydroxy-3-pinyl ketone, it is a chiral compound. The following is a description of its nature, use, formulation and safety information:
Nature:
(1S,2S,5S)-(-)-2-hydroxyy-3-pinanone is a colorless liquid with vanilla and fragrance. Its molecular formula is C10H16O and its molecular weight is 152.23g/mol. It has a density of 0.970 g/mL, a boiling point of 216-218 ° C, and an optical rotation of -58 °. It is soluble in alcohol and ether solvents.
Use:
(1S,2S,5S)-(-)-2-hydroxyy-3-pinanone is commonly used as a chiral catalyst and intermediate in organic synthesis. It can be used to synthesize chiral compounds in pharmaceuticals, perfumes and cosmetics. It can also be applied to the synthesis of biologically active natural products.
Method:
(1S,2S,5S)-(-)-2-hydroxyy-3-pinanone is generally prepared by chiral catalytic hydrogenation of dihydroketone or by using chiral starting materials. The specific preparation method varies depending on the experimental conditions and the requirements of the target product.
Safety Information:
(1S,2S,5S)-(-)-2-hydroxy-3-pinanone has low toxicity under normal use conditions. Its safe operation requires attention to prevent contact with eyes, skin and clothing. Appropriate protective gloves and goggles should be worn when using it. Fire and high temperatures should be avoided during storage and handling. In use, attention should be paid to well-ventilated places to avoid inhalation of its steam. If inadvertently ingested or inhaled too much, should promptly seek medical attention.
Nature:
(1S,2S,5S)-(-)-2-hydroxyy-3-pinanone is a colorless liquid with vanilla and fragrance. Its molecular formula is C10H16O and its molecular weight is 152.23g/mol. It has a density of 0.970 g/mL, a boiling point of 216-218 ° C, and an optical rotation of -58 °. It is soluble in alcohol and ether solvents.
Use:
(1S,2S,5S)-(-)-2-hydroxyy-3-pinanone is commonly used as a chiral catalyst and intermediate in organic synthesis. It can be used to synthesize chiral compounds in pharmaceuticals, perfumes and cosmetics. It can also be applied to the synthesis of biologically active natural products.
Method:
(1S,2S,5S)-(-)-2-hydroxyy-3-pinanone is generally prepared by chiral catalytic hydrogenation of dihydroketone or by using chiral starting materials. The specific preparation method varies depending on the experimental conditions and the requirements of the target product.
Safety Information:
(1S,2S,5S)-(-)-2-hydroxy-3-pinanone has low toxicity under normal use conditions. Its safe operation requires attention to prevent contact with eyes, skin and clothing. Appropriate protective gloves and goggles should be worn when using it. Fire and high temperatures should be avoided during storage and handling. In use, attention should be paid to well-ventilated places to avoid inhalation of its steam. If inadvertently ingested or inhaled too much, should promptly seek medical attention.
Last Update：2024-04-09 19:05:47
