(9H-芴-9-基)甲基4-(氨基甲基)哌啶-1-羧酸盐酸盐

(9H-芴-9-基)甲基4-(氨基甲基)哌啶-1-羧酸盐酸盐 - Names and Identifiers

Name	9H-fluoren-9-ylmethyl 4-(aminomethyl)piperidine-1-carboxylate hydrochloride
Synonyms	4-(AMINOMETHYL)-1-N-FMOC-PIPERIDINE 4-(Aminomethyl)-1-N-Fmoc-Piperidine 1-FMoc-4-(aMinoMethyl)piperidine HCl 4-(AMinoMethyl)-1-N-FMoc-piperidine HCl 1-Fmoc-4-(Aminomethyl)Piperidine hydrochloride 4-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID 9H-FLUOREN-9-YLMETHYL ESTER 9H-fluoren-9-ylmethyl 4-(aminomethyl)piperidine-1-carboxylate hydrochloride (9H-fluoren-9-yl)methyl 4-(aminomethyl)piperidine-1-carboxylate hydrochloride 4-(Aminomethyl)-1-piperidinecarboxylic acid 9H-fluoren-9-ylmethyl ester hydrochloride
CAS	391248-14-9
InChI	InChI=1/C21H24N2O2.ClH/c22-13-15-9-11-23(12-10-15)21(24)25-14-20-18-7-3-1-5-16(18)17-6-2-4-8-19(17)20;/h1-8,15,20H,9-14,22H2;1H

(9H-芴-9-基)甲基4-(氨基甲基)哌啶-1-羧酸盐酸盐 - Physico-chemical Properties

Molecular Formula	C21H24N2O2
Molar Mass	336.43
Boling Point	509.2°C at 760 mmHg
Flash Point	261.7°C
Vapor Presure	1.74E-10mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Sensitive	Irritant
MDL	MFCD02179398

(9H-芴-9-基)甲基4-(氨基甲基)哌啶-1-羧酸盐酸盐 - Risk and Safety

Hazard Class

IRRITANT

(9H-芴-9-基)甲基4-(氨基甲基)哌啶-1-羧酸盐酸盐 - Introduction

9H-fluoren-9-ylmethyl 4-(aminomethyl)piperidine-1-carboxylate hydrochloride is an organic compound whose chemical formula is C24H24ClNO2. It is a white solid soluble in organic solvents and is often used as a protecting group in peptide synthesis. It has the following characteristics:

1. properties: 9H-fluoren-9-ylmethyl 4-(aminomethyl)piperidine-1-carboxylate hydrochloride is a stable compound, not easy to decompose. It is relatively stable to light and humidity, but hydrolyzes under strong acid and alkali conditions.

2. use: it is mainly used for peptide synthesis of N-alpha-protecting group. It can protect the amino group, so that it does not react with other functional groups, so as to achieve the target peptide synthesis. After completion of the synthesis, the protecting group can be removed by appropriate conditions.

3. preparation method: 9H-fluoren-9-ylmethyl 4-(aminomethyl)piperidine-1-carboxylate hydrochloride can be obtained by reacting Fmoc-Cl (fluorocarbyl chloride) with 4-(aminomethyl)-piperidine under alkaline conditions. Subsequently, the hydrochloride salt form can be obtained by treatment with hydrochloric acid.

4. Safety Information: Under proper handling and storage conditions, 9H-fluoren-9-ylmethyl 4-(aminomethyl)piperidine-1-carboxylate hydrochloride is generally less toxic. However, as with any chemical, safe practices should be followed. Avoid direct contact with skin and eyes, and wear appropriate personal protective equipment when using. A well-ventilated laboratory environment should be maintained during processing.

Last Update：2024-04-10 22:29:15