(R)-DM-SEGPHOS(R)

(R)-DM-SEGPHOS(R) - Names and Identifiers

Name	(R)-(+)-DM-SEGPHOS
Synonyms	(R)-DM-SEGPHOS (R)-DM-SEGPHOS(R) (R)-(+)-DM-SEGPHOS (R)-(+)-DM-SEGPHOS(regR) (R)-(+)-DM-SEGPHOS(REGR)(R)-(+)-DM-SEGPHOS(REGR) (R)-(+)-5,5'-Bis[di(3,5-xylyl)phosphino]-4,4'-bi-1,3-benzodioxole 1,1'-[(4R)-[4,4'-Bi-1,3-benzodioxole]-5,5'-diyl]bis[1,1-bis(3,5-dimethylphenyl)phosphine]
CAS	850253-53-1

(R)-DM-SEGPHOS(R) - Physico-chemical Properties

Molecular Formula	C46H44O4P2
Molar Mass	722.8
Melting Point	256-261°C
Boling Point	816.9±65.0 °C(Predicted)
Appearance	Powder
Color	off white to pale yellow
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

(R)-DM-SEGPHOS(R) - Risk and Safety

WGK Germany

(R)-DM-SEGPHOS(R) - Introduction

(R)-( )-DM-SEGPHOS ((R)-( )-DM-SEGPHOS) is a chiral organophosphorus compound with the following properties:

Appearance: White crystalline solid
Molecular formula: C46H34P2
Molecular weight: 646.71g/mol
Melting point: 118-120°C

(R)-( )-DM-SEGPHOS can be used as a ligand in catalysts, mainly for catalyzing asymmetric synthesis reactions, especially in the presence of metal organic catalysts (such as palladium, platinum, ruthenium or rhodium). It is widely used in asymmetric hydrogenation, diazotization, olefin hydrogenation, asymmetric nucleophilic substitution, asymmetric reduction and other reactions.

The method for preparing (R)-( )-DM-SEGPHOS includes a two-step reaction. First, 3,5-xylitol reacts with Ph2PCl to obtain 3,5-xylylbis (diphenylphosphine) compound; then, it reacts with 4,4 '-bis (1,3-benzodione) under the catalysis of lead (II) salt to obtain the target product.

When using (R)-( )-DM-SEGPHOS, you need to pay attention to the following safety information:
-Appropriate laboratory safety measures must be taken, such as wearing personal protective equipment (e. g. gloves, glasses, protective clothing, etc.).
-Avoid skin contact and inhalation.
-Avoid contact with oxidants and strong acids.
-Should be operated in a well-ventilated place.
-Waste disposal is subject to local regulations.

Last Update：2024-04-10 22:29:15