(±)4-(氨基乙基)-1-(苯基甲基)-2-吡咯烷酮
NEBRACETAM
CAS: 116041-13-5
Molecular Formula: C12H16N2O
(±)4-(氨基乙基)-1-(苯基甲基)-2-吡咯烷酮 - Names and Identifiers
| Name | NEBRACETAM |
| Synonyms | WEB-1881 NEBRACETAM WEB-1881FU Nebracetamum Unii-T30038qi8n Nebracetamum [inn-latin] (±)-4-(Aminomethyl)-1-(phenylmethyl)-2-pyrrolidinone |
| CAS | 116041-13-5 |
(±)4-(氨基乙基)-1-(苯基甲基)-2-吡咯烷酮 - Physico-chemical Properties
| Molecular Formula | C12H16N2O |
| Molar Mass | 204.271 |
| Physical and Chemical Properties | Chemical Properties Nairacetam Fumarate (Nebracetam Fumarate):(C12H16N2O)2?C4H4O4. [97205-35-1]. Crystallization, melting point 192~194 ℃. Acute toxicity LD50 male and female rats (mg/kg):257,257 intravenous injection; 2884,3622 oral. |
| Use | Use of nootropic drugs. It has a cholinergic effect and has an affinity for cholinergic receptors, especially for M1, the receptor. |
(±)4-(氨基乙基)-1-(苯基甲基)-2-吡咯烷酮 - Upstream Downstream Industry
| Raw Materials | Fumaric acid |
(±)4-(氨基乙基)-1-(苯基甲基)-2-吡咯烷酮 - Production method
Method 1: Compound (I) and thionyl chloride are refluxed in methylene chloride to form chloride (II). Then it is condensed with potassium phthalamide in dimethylformamide, and the product (III) is reduced with hydrazine in ethanol to obtain nelacetam, which is neutralized with fumaric acid to obtain nelacetam fumarate.
Method 2: Compound (Ⅳ) is reacted with phosphorus oxychloride in hot dimethylformamide to dehydrate to obtain nitrile (V), and then hydrogenated and reduced under the catalysis of Raney nickel in ammonia-methanol mixture to obtain nelacetam, and neutralized with fumaric acid to obtain nelacetam fumarate.
Last Update：2024-04-10 22:29:15
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Spot supply
Product Name: NEBRACETAM Visit Supplier Webpage Request for quotationCAS: 116041-13-5
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
View History
(±)4-(氨基乙基)-1-(苯基甲基)-2-吡咯烷酮
3-Chlorophenacyl Bromide
2-Butanone, 1,4-bis(octyloxy)-
2-甲氧基-4-氟苯酚
1-溴甲基-2-三氟甲基苯
3-硝基-邻-甲苯酸甲酯
2-[[[3-甲基-1-氧代-4-(2,2,2-三氟乙氧基)-2-吡啶]甲基]亚硫酰基]苯并咪唑
4-硝基苯基硼酸
3-NITRO-P-TOLUENESULFONYL CHLORIDE
3-甲磺酰氨基苯硼酸
3-Chlorophenacyl Bromide
2-Butanone, 1,4-bis(octyloxy)-
2-甲氧基-4-氟苯酚
1-溴甲基-2-三氟甲基苯
3-硝基-邻-甲苯酸甲酯
2-[[[3-甲基-1-氧代-4-(2,2,2-三氟乙氧基)-2-吡啶]甲基]亚硫酰基]苯并咪唑
4-硝基苯基硼酸
3-NITRO-P-TOLUENESULFONYL CHLORIDE
3-甲磺酰氨基苯硼酸
Raw Materials for (±)4-(氨基乙基)-1-(苯基甲基)-2-吡咯烷酮