1-(2-BroMo-4-fluorophenyl)ethanone - Names and Identifiers
1-(2-BroMo-4-fluorophenyl)ethanone - Physico-chemical Properties
Molecular Formula | C8H6BrFO
|
Molar Mass | 217.04 |
Density | 1.535±0.06 g/cm3(Predicted) |
Melting Point | 48-50°C |
Boling Point | 150°C 12mm |
Flash Point | 110°C |
Vapor Presure | 0.0138mmHg at 25°C |
BRN | 2249797 |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.549 |
1-(2-BroMo-4-fluorophenyl)ethanone - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/38 - Irritating to eyes and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
Hazard Note | Irritant |
1-(2-BroMo-4-fluorophenyl)ethanone - Introduction
2-Bromo-4-fluoroacetophenone is an organic compound with the chemical formula C8H6BrFO. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 2-bromo-4-fluoroacetophenone is a colorless or slightly yellow liquid.
-Density: Its density is about 1.57g/cm³.
-Boiling point and melting point: Its boiling point is about 207-209°C, and its melting point is about -5°C.
-Solubility: 2-bromo-4-fluoroacetophenone is soluble in organic solvents such as ethanol and benzene.
Use:
-Industrial applications: It is often used as an intermediate in organic synthesis, such as the preparation of other compounds that can be used in the pharmaceutical, medical and pesticide fields.
-Medical application: 2-bromo-4-fluoroacetophenone is sometimes used for the preparation of drugs or the synthesis of compounds. It has certain antibacterial and antiviral activities.
Preparation Method:
2-Bromo-4-fluoroacetophenone is generally prepared by one of the following methods:
-Iodination reaction: 2-bromo-4-fluorophenyl ketone is reacted with hydrofluoric acid, and then a fluorine atom is replaced with a bromine atom using sodium iodide.
-nitroso reaction: 1-bromo-2-fluorobenzene and malononitrile are reacted to generate 2-bromo-4-fluorobenzonitrile, which is then hydrogenated to generate 2-bromo-4-fluoroacetophenone.
Safety Information:
2-Bromo-4-fluoroacetophenone is a chemical, so relevant safety procedures should be followed when handling and using. Some safety considerations are as follows:
-Chemicals should be kept away from fire and high temperature environment.
-Wear appropriate personal protective equipment such as lab gloves and goggles during operation.
-Avoid contact with skin and eyes, if there is contact should immediately rinse with plenty of water.
-use in a well-ventilated place, avoid inhalation of gas or steam.
-Waste disposal shall be carried out in accordance with local regulations.
Last Update:2024-04-09 20:49:11