1006-39-9
2-bromo-4-fluoroacetophenone
CAS: 1006-39-9
Molecular Formula: C8H6BrFO
1006-39-9 - Names and Identifiers
| Name | 2-bromo-4-fluoroacetophenone |
| Synonyms | 2-bromo-4-fluoroacetophenone 2'-BROMO-4'-FLUOROACETOPHENONE 2'-bromo-4'-fluoroacetophenone 2'-Bromo-4'-fluoroacetophenone 1-Acetyl-2-bromo-4-fluorobenzene 1-(2-BroMo-4-fluorophenyl)ethanone 1-(2-bromo-4-fluorophenyl)ethanone Ethanone,1-(2-bromo-4-fluorophenyl)- 1-(2-broMo-4-fluorophenyl)ethan-1-one 2'-Bromo-4'-fluoroacetophenone fandachem |
| CAS | 1006-39-9 |
| EINECS | 600-117-2 |
| InChI | InChI=1/C8H6BrFO/c1-5(11)7-3-2-6(10)4-8(7)9/h2-4H,1H3 |
1006-39-9 - Physico-chemical Properties
| Molecular Formula | C8H6BrFO |
| Molar Mass | 217.04 |
| Density | 1.535±0.06 g/cm3(Predicted) |
| Melting Point | 48-50°C |
| Boling Point | 150°C 12mm |
| Flash Point | 110°C |
| Vapor Presure | 0.0138mmHg at 25°C |
| BRN | 2249797 |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.549 |
1006-39-9 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/38 - Irritating to eyes and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| Hazard Note | Irritant |
1006-39-9 - Introduction
2-Bromo-4-fluoroacetophenone is an organic compound with the chemical formula C8H6BrFO. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 2-bromo-4-fluoroacetophenone is a colorless or slightly yellow liquid.
-Density: Its density is about 1.57g/cm³.
-Boiling point and melting point: Its boiling point is about 207-209°C, and its melting point is about -5°C.
-Solubility: 2-bromo-4-fluoroacetophenone is soluble in organic solvents such as ethanol and benzene.
Use:
-Industrial applications: It is often used as an intermediate in organic synthesis, such as the preparation of other compounds that can be used in the pharmaceutical, medical and pesticide fields.
-Medical application: 2-bromo-4-fluoroacetophenone is sometimes used for the preparation of drugs or the synthesis of compounds. It has certain antibacterial and antiviral activities.
Preparation Method:
2-Bromo-4-fluoroacetophenone is generally prepared by one of the following methods:
-Iodination reaction: 2-bromo-4-fluorophenyl ketone is reacted with hydrofluoric acid, and then a fluorine atom is replaced with a bromine atom using sodium iodide.
-nitroso reaction: 1-bromo-2-fluorobenzene and malononitrile are reacted to generate 2-bromo-4-fluorobenzonitrile, which is then hydrogenated to generate 2-bromo-4-fluoroacetophenone.
Safety Information:
2-Bromo-4-fluoroacetophenone is a chemical, so relevant safety procedures should be followed when handling and using. Some safety considerations are as follows:
-Chemicals should be kept away from fire and high temperature environment.
-Wear appropriate personal protective equipment such as lab gloves and goggles during operation.
-Avoid contact with skin and eyes, if there is contact should immediately rinse with plenty of water.
-use in a well-ventilated place, avoid inhalation of gas or steam.
-Waste disposal shall be carried out in accordance with local regulations.
Nature:
-Appearance: 2-bromo-4-fluoroacetophenone is a colorless or slightly yellow liquid.
-Density: Its density is about 1.57g/cm³.
-Boiling point and melting point: Its boiling point is about 207-209°C, and its melting point is about -5°C.
-Solubility: 2-bromo-4-fluoroacetophenone is soluble in organic solvents such as ethanol and benzene.
Use:
-Industrial applications: It is often used as an intermediate in organic synthesis, such as the preparation of other compounds that can be used in the pharmaceutical, medical and pesticide fields.
-Medical application: 2-bromo-4-fluoroacetophenone is sometimes used for the preparation of drugs or the synthesis of compounds. It has certain antibacterial and antiviral activities.
Preparation Method:
2-Bromo-4-fluoroacetophenone is generally prepared by one of the following methods:
-Iodination reaction: 2-bromo-4-fluorophenyl ketone is reacted with hydrofluoric acid, and then a fluorine atom is replaced with a bromine atom using sodium iodide.
-nitroso reaction: 1-bromo-2-fluorobenzene and malononitrile are reacted to generate 2-bromo-4-fluorobenzonitrile, which is then hydrogenated to generate 2-bromo-4-fluoroacetophenone.
Safety Information:
2-Bromo-4-fluoroacetophenone is a chemical, so relevant safety procedures should be followed when handling and using. Some safety considerations are as follows:
-Chemicals should be kept away from fire and high temperature environment.
-Wear appropriate personal protective equipment such as lab gloves and goggles during operation.
-Avoid contact with skin and eyes, if there is contact should immediately rinse with plenty of water.
-use in a well-ventilated place, avoid inhalation of gas or steam.
-Waste disposal shall be carried out in accordance with local regulations.
Last Update：2024-04-09 20:49:11
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Spot supply
Product Name: 2'-Bromo-4'-fluoroacetophenone Visit Supplier Webpage Request for quotationCAS: 1006-39-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2'-Bromo-4'-fluoroacetophenone Visit Supplier Webpage Request for quotationCAS: 1006-39-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
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